| [1] |
McIntire JJ, Umetsu SE, Akbari O, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family[J]. Nat Immunol, 2001, 2(12): 1109-1116.
|
| [2] |
Umetsu SE, Lee WL, McIntire JJ, et al. TIM-1 induces T cell activation and inhibits the development of peripheral tolerance[J]. Nat Immunol, 2005, 6(5): 447-454.
|
| [3] |
Meyers JH, Chakravarti S, Schlesinger D, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation[J]. Nat Immunol, 2005, 6(5): 455-464.
|
| [4] |
Mariat C, Sánchez-Fueyo A, Alexopoulos SP, et al. Regulation of T cell dependent immune responses by TIM family members[J]. Philos Trans R Soc Lond B Biol Sci, 2005, 360(1461): 1681-1685.
|
| [5] |
Monney L, Sabatos CA, Gaglia JL, et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease[J]. Nature, 2002, 415(6871): 536-541.
|
| [6] |
Sabatos CA, Chakravarti S, Cha E, et al. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance[J]. Nat Immunol, 2003, 4(11): 1102-1110.
|
| [7] |
Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, et al. Soluble T cell immunoglobulin mucin domain 3 is shed from CD8＋T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression[J]. J Virol, 2015, 89(7): 3723-3736.
|
| [8] |
Zhu C, Anderson AC, Schubart A, et al. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity[J]. Nat Immunol, 2005, 6(12): 1245-1252.
|
| [9] |
Cai XZ, Huang WY, Qiao Y, et al. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus[J]. Braz J Med Biol Res, 2015, 48(1): 77-82.
|
| [10] |
Wang S, Zhu X, Xu Y, et al. Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4＋T cells to induce type 2 helper T cell (Th2) bias at the maternal-fetal interface[J]. Hum Reprod, 2016, 31(4): 700-711.
|
| [11] |
Dolina JS, Braciale TJ, Hahn YS. Liver-primed CD8＋T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice[J]. Hepatology, 2014, 59(4): 1351-1365.
|
| [12] |
Zhao J, Lei Z, Liu Y, et al. Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity[J]. J Immunol, 2009, 182(10): 6618-6624.
|
| [13] |
Maurya N, Gujar R, Gupta M, et al. Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton′s tyrosine kinase and c-Src[J]. J Immunol, 2014, 193(7): 3417-3425.
|
| [14] |
Anderson AC. Tim-3: an emerging target in the cancer immunotherapy landscape[J]. Cancer Immunol Res, 2014, 2(5): 393-398.
|
| [15] |
Chiba S, Baghdadi M, Akiba H, et al. Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1[J]. Nat Immunol, 2012, 13(9): 832-842.
|
| [16] |
Wu J, Liu C, Qian S, et al. The expression of Tim-3 in peripheral blood of ovarian cancer[J]. DNA Cell Biol, 2013, 32(11): 648-653.
|
| [17] |
Guo Z, Cheng D, Xia Z, et al. Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer[J]. J Transl Med, 2013, 11(1): 215.
|
| [18] |
Cao Y, Zhou X, Huang X, et al. Tim-3 expression in cervical cancer promotes tumor metastasis[J]. PLoS One, 2013, 8(1): e53834.
|
| [19] |
周晓曦，李钦璐，黄闪，等. Tim-3在宫颈癌组织中的表达及其与恶性进展的关系[J]. 肿瘤防治研究，2012, 39(11): 1353-1356.
|
| [20] |
Tripathi S, Chabtini L, Dakle PJ, et al. Effect of TIM-3 blockade on the immunophenotype and cytokine profile of murine uterine NK cells[J]. PLoS One, 2015, 10(4): e0123439.
|
| [21] |
Ashkar AA, Black GP, Wei Q, et al. Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy[J]. J Immunol, 2003, 171(6): 2937-2944.
|
| [22] |
Chabtini L, Mfarrej B, Mounayar M, et al. TIM-3 regulates innate immune cells to induce fetomaternal tolerance[J]. J Immunol, 2013, 190(1): 88-96.
|
| [23] |
Wang SC, Li YH, Piao HL, et al. PD-1 and Tim-3 pathways are associated with regulatory CD8＋T-cell function in decidua and maintenance of normal pregnancy[J]. Cell Death Dis, 2015, 6(5): e1738.
|
| [24] |
Wu M, Zhu Y, Zhao J, et al. Soluble costimulatory molecule sTim3 regulates the differentiation of Th1 and Th2 in patients with unexplained recurrent spontaneous abortion[J]. Int J Clin Exp Med, 2015, 8(6): 8812-8819.
|
| [25] |
Saito S, Sakai M, Sasaki Y, et al. Quantitative analysis of peripheral blood Th0, Th1, Th2, and the Th1∶Th2 cell ratio during normal human pregnancy and preeclampsia[J]. Clin Exp Immunol, 1999, 117(3): 550-555.
|
| [26] |
Saito S, Nakashima A, Shima T, et al. Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy[J]. Am J Reprod Immunol, 2010, 63(6): 601-610.
|
| [27] |
Miko E, Meggyes M, Bogar B, et al. Involvement of galectin-9/TIM-3 pathway in the systemic inflammatory response in early-onset preeclampsia[J]. PLoS One, 2013, 8(8): e71811.
|
| [28] |
Miko E, Manfai Z, Meggyes M, et al. Possible role of natural killer and natural killer T-like cells in implantation failure after IVF[J]. Reprod Biomed Online, 2010, 21(6): 750-756.
|
| [29] |
van den Heuvel MJ, Hatta K, Peralta CG, et al. CD56＋cells are recruited to the uterus in two waves: at ovulation and during the first 2 weeks after missed menses[J]. Am J Reprod Immunol, 2008, 59(2): 90-98.
|
| [30] |
Tzianabos AO, Holsti MA, Zheng XX, et al. Functional Th1 cells are required for surgical adhesion formation in a murine model[J]. J Immunol, 2008, 180(10): 6970-6976.
|
| [31] |
Peng B, Lu C, Tang L, et al. Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with Chlamydia muridarum[J]. BMC Infect Dis, 2011, 11(1): 347.
|
| [32] |
Jayaraman P, Sada-Ovalle I, Beladi S, et al. Tim3 binding to galectin-9 stimulates antimicrobial immunity[J]. J Exp Med, 2010, 207(11): 2343-2354.
|