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中华妇幼临床医学杂志(电子版) ›› 2017, Vol. 13 ›› Issue (03) : 249 -255. doi: 10.3877/cma.j.issn.1673-5250.2017.03.001

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早产儿胃肠外营养相关性胆汁淤积的研究现状
钟美娇1, 薛辛东1,()   
  1. 1. 110004 沈阳,中国医科大学附属盛京医院新生儿科
  • 收稿日期:2017-03-20 修回日期:2017-05-08 出版日期:2017-06-01
  • 通信作者: 薛辛东

Research status of parenteral nutrition associated cholestasis

Meijiao Zhong1, Xindong Xue1,()   

  1. 1. Department of Neonatology, Shengjing Hospital of Chinese Medical University, Shenyang 110004, Liaoning Province, China
  • Received:2017-03-20 Revised:2017-05-08 Published:2017-06-01
  • Corresponding author: Xindong Xue
  • About author:
    Corresponding author: Xue Xindong, Email:
引用本文:

钟美娇, 薛辛东. 早产儿胃肠外营养相关性胆汁淤积的研究现状[J]. 中华妇幼临床医学杂志(电子版), 2017, 13(03): 249-255.

Meijiao Zhong, Xindong Xue. Research status of parenteral nutrition associated cholestasis[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2017, 13(03): 249-255.

胃肠外营养(PN)导致的胃肠外营养相关性胆汁淤积(PNAC)是早产儿常见的一种并发症,其病因复杂,包括早产和低出生体重、长时间禁食、静脉营养、感染等。目前临床对于PNAC尚无特效的治疗手段,但早期的胃肠内营养(EN)、改善PN溶液配方及微生态制剂等,对于预防早产儿PNAC发生具有重要意义。

Parenteral nutrition associated cholestasis (PNAC) leaded by parenteral nutrition (PN) is one of the most common complications in preterm infants. The etiologies of PNAC are complex, including preterm, low birth weight, long duration of fast, PN, infection and so on. As to PNAC, there is no special treatment currently, but it is very important to prevent PNAC by early enteral nutrition (EN), regulating formula of PN solution, using new lipid emulsion and supplement of probiotics.

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