Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2018, Vol. 14 ›› Issue (05): 497 -502. doi: 10.3877/cma.j.issn.1673-5250.2018.05.001

Special Issue:

Editorial

Nutritious supplement for the males preparing for childbirth

Baojun Wang1, Le Ma1,(), Linlin Wang2   

  1. 1. Department of Urology Surgery, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China
    2. Reproductive Healthcare Institute of Peking University, Beijing 100006, China
  • Received:2018-05-23 Revised:2018-09-09 Published:2018-10-01
  • Corresponding author: Le Ma
  • About author:
    Corresponding author: Ma Le, Email:
  • Supported by:
    National Natural Science Foundation of China for Youth(81202215)

With the accelerated pace of life, changes in diet, accumulation of bad habits, increased mental stress and environmental deterioration have posed a great threat to males′ health. Infertility has become a common disease with high incidence. Infertile women or men of childbearing age and pregnant couples often hope that doctors can give them dietary guidance. At present, there are many studies on the rational nutrition supplement for women before pregnancy, and there have been many progresses. However, there are few studies on the rational nutrition supplement for men preparing for childbirth. This paper summarizes some nutrients related to male fertility in the current studies, such as minerals (zinc, iron, calcium, magnesium, selenium), vitamins (vitamin A, B9, B12, C, D and E), and other important auxiliary nutrients (L-carnitine, lycopene, amino acids, coenzyme Q10, fructose, citric acid), hoping to give guidance to the males preparing for childbirth.

[1]
Fallah A,Mohammad-Hasani A,Colagar AH. Zinc is an essential element for male fertility: a review of Zn Roles in men′s health, germination, sperm quality, and fertilization[J]. J Reprod Infertil, 2018, 19(2): 69-81.
[2]
Wang YX,Wang P,Feng W, et al. Relationships between seminal plasma metals/metalloids and semen quality, sperm apoptosis and DNA integrity[J]. Environ Pollut, 2017, 224: 224-234.
[3]
Khan MS,Zaman S,Sajjad M, et al. Assessment of the level of trace element zinc in seminal plasma of males and evaluation of its role in male infertility[J]. Int J Appl Basic Med Res, 2011, 1(2): 93-96.
[4]
Hashemi MM,Behnampour N,Nejabat M, et al. Impact of seminal plasma trace elements on human sperm motility parameters[J]. Rom J Intern Med, 2018, 56(1): 15-20.
[5]
袁玉玶,王丽,魏学文,等. 男性不育症精液微量元素与精子密度及精子活动力的关系[J]. 国际检验医学杂志,2015, 36(23): 3409-3410.
[6]
Cao Z,Shao B,Xu F, et al. Protective effect of selenium on aflatoxin B1-induced testicular toxicity in mice[J]. Biol Trace Elem Res, 2017, 180(2): 233-238.
[7]
Marzec-Wróblewska U,Kamiński P,Łakota P, et al. The employment of IVF techniques for establishment of sodium, copper and selenium impact upon human sperm quality[J]. Reprod Fertil Dev, 2015, 28(10): 1518-1525.
[8]
Zhou Q,Nie R,Li Y, et al. Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes[J]. Biol Reprod, 2008, 79(1): 35-42.
[9]
Malivindi R,Rago V,De Rose D, et al. Influence of all-trans retinoic acid on sperm metabolism and oxidative stress: its involvement in the physiopathology of varicocele-associated male infertility[J]. J Cell Physiol, 2018, 233(12): 9526-9537.
[10]
Najafipour R,Moghbelinejad S,Aleyasin A, et al. Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms[J]. Andrology, 2017, 5(4): 704-710.
[11]
Mfady DS,Sadiq MF,Khabour OF, et al. Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population[J]. Gene, 2014, 536(1): 40-44.
[12]
Irani M,Amirian M,Sadeghi R, et al. The effect of folate and folate plus Zinc supplementation on endocrine parameters and sperm characteristics in sub-fertile men: a systematic review and Meta-analysis[J]. Urol J, 2017, 14(5): 4069-4078.
[13]
Ly L,Chan D,Aarabi M, et al. Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation[J]. Mol Hum Reprod, 2017, 23(7): 461-477.
[14]
Gual-Frau J,Abad C,Amengual MJ, et al. Oral antioxidant treatment partly improves integrity of human sperm DNA in infertile grade Ⅰ varicocele patients[J]. Hum Fertil (Camb), 2015, 18(3): 225-229.
[15]
Rafiee B,Morowvat MH,Rahimi-Ghalati N. Comparing the effectiveness of dietary vitamin C and exercise interventions on fertility parameters in normal obese men[J]. Urol J, 2016, 13(2): 2635-2639.
[16]
Cyrus A,Kabir A,Goodarzi D, et al. The effect of adjuvant vitamin C after varicocele surgery on sperm quality and quantity in infertile men: a double blind placebo controlled clinical trial[J]. Int Braz J Urol, 2015, 41(2): 230-238.
[17]
Hofer D,Münzker J,Schwetz V, et al. Testicular synthesis and vitamin D action[J]. J Clin Endocrinol Metab, 2014, 99(10): 3766-3773.
[18]
Abbasihormozi S,Kouhkan A,Alizadeh AR, et al. Association of vitamin D status with semen quality and reproductive hormones in Iranian subfertile men[J]. Andrology, 2017, 5(1): 113-118.
[19]
宾彬,陆海旺,王杰,等. 抗氧化中西药治疗男性不育症研究进展[J]. 四川中医,2013, 36(8): 185-188.
[20]
Mohammadi S,Jalali M,Nikravesh MR, et al. Effects of vitamin-E treatment on CatSper genes expression and sperm quality in the testis of the aging mouse[J]. Iran J Reprod Med, 2013, 11(12): 989-998.
[21]
姜辉,邓春华,商学军,等. 维生素E在男性不育中临床应用专家共识(2014版)[J]. 中华男科学杂志,2015, 21(3): 277-279.
[22]
Walczak-Jedrzejowska R,Wolski JK,Slowikowska-Hilczer J. The role of oxidative stress and antioxidants in male fertility[J]. Cent European J Urol, 2013, 66(1): 60-67.
[23]
Abad C,Amengual MJ,Gosálvez J, et al. Effects of oral antioxidant treatment upon the dynamics of human sperm DNA fragmentation and subpopulations of sperm with highly degraded DNA[J]. Andrologia, 2013, 45(3): 211-216.
[24]
易湛苗,董淑杰,翟所迪,等. 左卡尼汀及其衍生物临床应用的循证证据及评价[J]. 中国药物应用与监测,2013, 10(2): 71-74.
[25]
牛玉森. 左旋肉碱治疗男性不育症有效性的Meta分析[J]. 兰州大学学报(医学版), 2014, 40(2): 41-46.
[26]
Tvrdá E,Kovácˇik A,Tusˇimová E, et al. Antioxidant efficiency of lycopene on oxidative stress - induced damage in bovine spermatozoa[J]. J Anim Sci Biotechnol, 2016, 7(1): 50.
[27]
Ghyasvand T,Goodarzi MT,Amiri I, et al. Serum levels of lycopene, beta-carotene, and retinol and their correlation with sperm DNA damage in normospermic and infertile men[J]. Int J Reprod Biomed (Yazd), 2015, 13(12): 787-792.
[28]
徐胜旗. 不育症患者与正常人群血浆、精浆中番茄红素浓度差异性研究[D]. 长春:吉林大学,2015.
[29]
Chen JQ,Li YS,Li ZJ, et al. Dietary L-arginine supplementation improves semen quality and libido of boars under high ambient temperature[J]. Animal, 2018, 12(8): 1611-1620.
[30]
Khiabani AB,Moghaddam G,Kia HD. Effects of adding different levels of glutamine to modified Beltsville extender on the survival of frozen rooster semen[J]. Anim Reprod Sci, 2017, 184: 172-177.
[31]
Dong HJ,Wu D,Xu SY, et al. Effect of dietary supplementation with amino acids on boar sperm quality and fertility[J]. Anim Reprod Sci, 2016, 172: 182-189.
[32]
Safarinejad MR. The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study[J]. Int Urol Nephrol, 2012, 44(3): 689-700.
[33]
Lafuente R,González-Comadrán M,Solà I, et al. Coenzyme Q10 and male infertility: a Meta-analysis[J]. J Assist Reprod Genet, 2013, 30(9): 1147-1156.
[34]
田小燕. 不同类型精浆抗精子抗体对精液质量的影响[J]. 中国当代医药,2014, 21(1): 129-130, 133.
[35]
尹彪,刘红杰,赵明,等. 精浆中锌、果糖和肉碱含量与精液参数的关系[J]. 中华男科学杂志,2013, 19(11): 1051-1053.
[36]
李耀雄,梁洁玲,贺美,等. 探讨精浆果糖及精液抗精子抗体与精子参数关系对男性不育患者的影响[J/CD]. 临床医药文献电子杂志,2016, 3(37): 7355-7356.
[37]
毛冉,李清泉,石剑华,等. 不同糖类稀释液对低温保存杜泊羊鲜精的影响[J]. 家畜生态学报,2015, 36(12): 24-28.
[38]
Adames MS,de Toledo CP,Neumann G, et al. Optimization of the sperm: oocyte ratio and sperm economy in the artificial reproduction of Rhamdia quelen using fructose as a sperm motility modulator[J]. Anim Reprod Sci, 2015, 161: 119-128.
[39]
彭冰洁,谢友元,李辉玉,等. 394例男性不育患者前列腺功能检测与精液常规参数分析[J]. 世界最新医学信息文摘,2016, 16(86): 26-27.
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