Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2023, Vol. 19 ›› Issue (04): 403 -409. doi: 10.3877/cma.j.issn.1673-5250.2023.04.005

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Current research status on predictors of lymphatic vascular invasion in patients with endometrial carcinoma

Chunying Han, Tingting Wang, Yanyan Li, Jinxia Piao()   

  1. Department of Gynecology and Oncology-3, Jilin Provincial Cancer Hospital, Changchun 130012, Jilin Province, China
  • Received:2023-01-08 Revised:2023-07-01 Published:2023-08-01
  • Corresponding author: Jinxia Piao
  • Supported by:
    Science and Technology Development Plan Project of Jilin Province(20200403096SF)

Lymphatic vascular infiltration (LVSI) is one of the prognostic factors for patients with endometrial cancer(EC), but LVSI mainly depends on pathological analysis of surgical specimens, which has certain limitations. In recent years, preliminary progress has been made in the prediction of LVSI, such as molecular level detection, including DNA, RNA and related protein detection, which can help to predict LVSI status. Predictive models developed from clinical data can also aid in clinical judgment LVSI in patients with EC. The author intends to review the latest research progresses on molecular prediction, immunohistochemistry prediction, and related risk model prediction of LVSI status in patients with EC, with the aim of providing reference for clinical diagnosis and treatment planning of EC.

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