Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2017, Vol. 13 ›› Issue (02): 144 -148. doi: 10.3877/cma.j.issn.1673-5250.2017.02.005

Special Issue:

Editorial

Research progress of 8-hydroxy-2′-deoxyguanosine in oxidative stress and childhood-related diseases

Xi Huang1, Wentao Peng1, Biru Luo1,()   

  1. 1. Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2016-12-01 Revised:2017-01-22 Published:2017-04-01
  • Corresponding author: Biru Luo
  • About author:
    Corresponding author: Luo Biru, Email:

As we know, 8-hydroxy-2′-deoxyguanosine (8-OHdG) is one of the oxidative damage products of DNA. The level of 8-OHdG can reflect the degree of oxidative damage in the body, and it is recognized internationally as one of new indicators and biomarkers for evaluating DNA oxidative damage and oxidative stress (OS) state. This study will focus on the detection method of 8-OHdG, and the research progress of 8-OHdG in OS and childhood-related diseases, in order to provide a reference for the diagnosis and treatment of those disease.

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