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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2023, Vol. 19 ›› Issue (05): 522 -529. doi: 10.3877/cma.j.issn.1673-5250.2023.05.005

Forum

Current research status on adverse pregnancy outcomes of maternal and infant in pregnant women with asthma

Haoyuan Yang, Jie Gong†(), Qingwei Zou, Hang Ruan   

  1. Department of Obstetrics, Shiyan Renmin Hospital, Affiliated to Hubei University of Medicine, Shiyan 442000, Hubei Province, China
    Department of Pharmaceutical, Shiyan Renmin Hospital, Affiliated to Hubei University of Medicine, Shiyan 442000, Hubei Province, China
    Department of Critical-Care Medicine, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
  • Received:2023-03-30 Revised:2023-08-28 Published:2023-10-01
  • Corresponding author: Jie Gong
  • Supported by:
    Project of Scientific Research of Health Commission of Hubei Province(WJ2019F053)
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Bronchial asthma, or simply being called as asthma, is a prevalent respiratory disorder among pregnant women. Globally, 8% to 13% women currently suffer from asthma, with 3% to 12% experiencing acute asthma episodes during pregnancy. Acute exacerbations of pregnant women with asthma may adversely affect foetal growth and development and have been associated with adverse foetal pregnancy outcomes, such as low birth weight infant, small for gestational age infant and preterm birth. Delving into effects of asthma during pregnancy on both mother and fetus can shed light on physiological mechanisms underlying asthma attacks, identify comorbidities, and facilitate timely treatment to prevent adverse outcomes. This review primarily focuses on four aspects. ①The definition, diagnosis, and monitoring of asthma during pregnancy. ② Respiratory mechanisms influencing asthma development in pregnant women. ③ Common adverse maternal and fetal pregnancy outcomes in pregnant women with asthma. ④ Obstetric management of pregnant women with asthma. Its aim is to provide a valuable reference for further clinical studies on asthma during pregnancy.

Key words: Asthma, pregnancy, Pregnancy outcome, maternal-child, Pregnancy complications, Glucocorticoid, Obstetric management, Asthma exacerbations, Infant, Small for gestational age, Asthma control during pregnancy
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