Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2019, Vol. 15 ›› Issue (01): 98 -102. doi: 10.3877/cma.j.issn.1673-5250.2019.01.017

Special Issue:

Review

Research progress of diagnosis and treatment on group B Streptococcus infection in perinatal period

Zhenzhen Wang1, Dan Lu2,(), Min Jiang2   

  1. 1. Dalian Medical University, Dalian 116044, Liaoning Province, China
    2. Medical College of Yangzhou University, Yangzhou 225009, Jiangsu Province, China
  • Received:2018-04-22 Revised:2018-12-17 Published:2019-02-01
  • Corresponding author: Dan Lu
  • About author:
    Corresponding author: Lu Dan, Email:
  • Supported by:
    Research Project of Maternal and Child Health of Jiangsu Provincial Commission of Health and Family Planning(F201663); General Program of Social Development of Science and Technology in Yangzhou City(YZ2017075)

Group B Streptococcus (GBS) is one of the important pathogens in adverse effects on pregnancy outcomes. GBS is also the leading cause of complications such as neonatal sepsis and meningitis and death of perinatal infants. There are ten different serotypes of GBS infection. GBS screening for pregnant women in perinatal period can provide references for clinicians taking intrapartum antibacterial prophylaxis (IAP) measures timely on pregnant women to prevent perinatal GBS infection, and effectively reduce infection rate of perinatal GBS. As a simple and safe method to prevent GBS infection, GBS vaccines have been paid more and more attention. GBS vaccines are currently the most prospective measure to prevent neonatal GBS infection through maternal immunity, but they have no preventive effects on neonatal-late onset GBS infection. This article focuses on adverse pregnancy outcomes, risk factors, effects of regional differences, diagnosis, treatment caused by perinatal GBS infection and current research development of GBS vaccines.

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