分析四川汶川地震极重灾区再生育妇女妊娠及流产情况，探讨地震灾害、年龄及其他因素对再生育妇女妊娠及妊娠结局的影响。

选取2008年5月至2010年3月来自汶川地震极重灾区的860例有再生育意愿的妇女为研究对象，按年龄将其分为<35岁组(n＝323)、35~39岁组(n＝270)和≥40岁组(n＝267)。采取回顾性分析法对其妊娠、妊娠结局及其他影响因素进行统计学分析(本研究遵循的程序符合本服务站人体试验委员会所制定的伦理学标准，得到该委员会批准，分组征得受试对象本人的知情同意，并与之签署临床研究知情同意书)。

860例再生育妇女中，成功妊娠为704例，妊娠率为81.86%(704/860)，而自然流产率为19.32%(136/704)，且自然流产率随妊娠妇女年龄增大而增高。≥40岁组再生育妇女妊娠率低于<35岁组及35~39岁组，差异均有统计学意义(P<0.05)。

四川汶川地震极重灾区再生育妇女，由于综合因素影响，妊娠自然流产发生率明显高于育龄期女性自然流产发生率[19.32% vs.(10%~15%)]。及时、有效的综合预防和干预，是提高其妊娠率、降低自然流产率的必要措施。

To analyze the pregnancy and spontaneous abortion of the refertility women in the worst-hit area of Wenchuan earthquake in Sichuan province, and explore the influence of the earthquake disaster, age and other factors on the pregnancy and the result of pregnancy.

From May 2008 to March 2010, the whole service work of refertility in the 5·12 worst-hit area of Wenchuan earthquake in Sichuan province were summed up, and 860 women who had the willing of refertility were included in the study. They were divided into age<35 years old group (n=323), 35-39 years old group(n=270), and ≥40 years old group(n=267) according to their age. Analyzed their pregnancy, results of pregnancy and other influencing factors by retrospective method. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Birth Control Service Station of Mianzhu.

Among these 860 women, 704 cases had successful pregnancy. The pregnant rate was 81.86%(704/860). Meanwhile, the spontaneous abortion rate was 19.32%(136/704), and the older they were, the higher spontaneous abortion rate was. The pregnant rates of the refertility women in ≥40 years old group was obviously lower than those of <35 years old group and 35-39 years old group(P<0.05).

The spontaneous abortion rates of the refertility women in the earthquake disaster area are obviously higher than those of normal pregnancy women[19.32%vs.(10%-15%)]because of the comprehensive factors. So immediately and effective comprehensive measures of prevention and intervention were necessary to improve the pregnancy rate and decline the spontaneous abortion rate.