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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2025, Vol. 21 ›› Issue (03): 251 -256. doi: 10.3877/cma.j.issn.1673-5250.2025.03.001

Expert Insight

Strategic reflections on child development research

Hanmin Liu†()   

  1. Department of Pediatric Respiratory and Immunology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, NHC Key Laboratory of Chronobiology (Sichuan University), Chengdu 610041, Sichuan Province, China; Department of Pediatric Pulmonology and Immunology, WCSUH-Tianfu·Sichuan Provincial Children′s Hospital, Meishan 620010, Sichuan Province, China; The Joint Laboratory for Lung Development and Related Diseases of West China Second University Hospital (Sichuan University) and School of Life Sciences of Fudan University, Chengdu 610041, Sichuan Province, China; Sichuan Birth Defects Clinical Research Center, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2025-05-12 Revised:2025-05-25 Published:2025-06-01
  • Corresponding author: Hanmin Liu
  • Supported by:
    National Natural Science Foundation of China (NSFC) Regional Innovation and Development Joint Project: Decoding the Role and Mechanism of " Vascular-Guided Microenvironment" in Promoting Postnatal Lung Development after Premature Birth(U21A20333); Major Research and Development Program of the Department of Science and Technology of Tibet Autonomous Region: Research on Early Warning Technologies and Intervention Strategies for Major Respiratory Diseases in Plateau Pediatric Populations(2025); Tibet Autonomous Region Key R&D Program: Chronobiological Study of Lung Developmental Adaptation Cohorts in Plateau Infants and Young Children(XZ202501ZY0116)
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Development serves as the central tenet of pediatric research. High-level conceptualization of the cognitive dimensions and research strategies in development is crucial for exploring the origins of life and improving disease management. This article focuses on the conceptual definitions, core connotations, and clinical practice challenges in child development research, emphasizing the need to dynamically and systematically restructure the frameworks for studying child health and disease through a developmental mindset, thereby strengthening holistic research in pediatrics.

Key words: Child development, Developmental origins of health and disease, DOHaD theory, Hygiene hypothesis, Pediatric pharmacology, Microecology
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