Role of nutrition intervention strategy based on mobile medical APP on nutritional status and physical development of premature infants after discharge from hospital

doi:10.3877/cma.j.issn.1673-5250.2021.04.015

Objective

To investigate the role of nutrition intervention strategies based on mobile medical APP on nutritional status and physical development of premature infants after discharge from hospital.

Methods

A total of 60 premature infants in neonatal ward of Second Nanning People′s Hospital and Shenzhen Shajing Hospital Affiliated to Guangzhou Medical University from January 2018 to December 2020 were selected as research subjects. They were divided into study group (n=30) and control group (n=30) by random digits table method. Premature infants in study group received nutrition intervention strategy by mobile medical APP for 6 months, while premature infants in control group received routine follow-up by phone call for 6 months. The growth and development indicators of premature infants, score of Children′s Developmental Checklist, biochemical indicators, and incidence of neonatal diseases were compared between two groups by independent-samples t test and chi-square test. There were no statistically significant differences between two groups in general clinical data such as gender composition ratio, gestational age at birth, and birth weight (P>0.05). This study was approved by the Medical Ethics Committee of Second Nanning People′s Hospital (approval No. 20180108), and each guardian of premature infants signed an informed consent form for clinical research.

Results

①After intervention, body length, head circumference and body weight of premature infants in study group were (66.7±6.4) cm, (7.7±2.2) kg, (42.0±3.4) cm respectively, which were all better than those (60.3±5.3) cm in control group, (7.0±1.5) kg, (39.2±2.5) cm in control group, and all differences were statistically significant (t=4.187, P<0.001; t=2.291, P=0.029; t=3.575, P<0.001). ②After intervention, scores of Intelligence Scale and Exercise Scale in study group were (91.1±10.4) scores and (48.6±5.2) scores, which were higher than those (78.2±8.2) scores, (42.3±4.1) scores in control group, and both differences were statistically significant (t=5.287, 5.235; P<0.001). ③After intervention, levels of serum pre-albumin (PA) and retinol-binding proteins (RBP) in study group were (136.1±8.5) mg/L, (140.7±16.9) mg/L respectively, which were significantly higher than those (120.3±7.0) mg/L, (126.6±14.3) mg/L in control group, and both differences were statistically significant (t=7.808, 3.498; P<0.001). ④The incidence of disease in study group was 10.0% (3/30), which was significantly lower than that 36.7% (11/30) in control group, and the difference was statistically significant (χ²=5.583, P=0.016).

Conclusions

Nutrition intervention strategy based on mobile medical APP can significantly improve nutritional status of premature infants after discharge from hospital, promote their growth and development, reduce incidence of neonatal diseases, and improve their quality of life.

Key words: Nutritional status, Mobile medical APP, Nutrition management, Child nutrition sciences, Child development, Growth and development, Infant, premature

表1 2组早产儿干预前、后生长发育指标比较(±s)

组别	例数	身高(cm)		体重(kg)		头围(cm)
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后
研究组	30	34.0±4.1	66.7±6.4	1.9±0.4	7.7±2.2	28.7±2.3	42.0±3.4
对照组	30	33.1±4.0	60.3±5.3	2.0±0.3	7.0±1.5	29.0±2.2	39.2±2.5
t值		0.887	4.187	0.215	2.291	1.045	3.575
P值		0.375	<0.001	0.830	0.029	0.907	<0.001

表1 2组早产儿干预前、后生长发育指标比较(±s)

组别	例数	身高(cm)		体重(kg)		头围(cm)
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后
研究组	30	34.0±4.1	66.7±6.4	1.9±0.4	7.7±2.2	28.7±2.3	42.0±3.4
对照组	30	33.1±4.0	60.3±5.3	2.0±0.3	7.0±1.5	29.0±2.2	39.2±2.5
t值		0.887	4.187	0.215	2.291	1.045	3.575
P值		0.375	<0.001	0.830	0.029	0.907	<0.001

表2 2组早产儿干预前、后智能发育评分及血清PA、PBP水平比较(±s)

组别	例数	《智能量表》评分(分)		《运动量表》评分(分)		PA(mg/L)		RBP(mg/L)
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
研究组	30	57.0±7.1	91.1±10.4	23.3±2.6	48.6±5.2	90.3±5.7	136.1±8.5	102.7±12.0	140.7±16.9
对照组	30	56.7±7.2	78.2±8.2	23.2±2.6	42.3±4.1	90.0±5.9	120.3±7.0	102.2±11.7	126.6±14.3
t值		0.145	5.287	0.089	5.235	0.140	7.808	0.160	3.498
P值		0.884	<0.001	0.929	<0.001	0.889	<0.001	0.873	<0.001

表2 2组早产儿干预前、后智能发育评分及血清PA、PBP水平比较(±s)

组别	例数	《智能量表》评分(分)		《运动量表》评分(分)		PA(mg/L)		RBP(mg/L)
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
研究组	30	57.0±7.1	91.1±10.4	23.3±2.6	48.6±5.2	90.3±5.7	136.1±8.5	102.7±12.0	140.7±16.9
对照组	30	56.7±7.2	78.2±8.2	23.2±2.6	42.3±4.1	90.0±5.9	120.3±7.0	102.2±11.7	126.6±14.3
t值		0.145	5.287	0.089	5.235	0.140	7.808	0.160	3.498
P值		0.884	<0.001	0.929	<0.001	0.889	<0.001	0.873	<0.001

表3 2组早产儿疾病发生情况比较[例数(%)]

组别	例数	感染	视网膜病	慢性肺损伤	贫血	合计
研究组	30	2(6.7)	0(0)	0(0)	1(3.3)	3(10.0)
对照组	30	5(16.7)	1(3.3)	2(6.7)	3(10.0)	11(36.7)
χ²值		—	—	—	—	5.583
P值		—	—	—	—	0.016

表3 2组早产儿疾病发生情况比较[例数(%)]

组别	例数	感染	视网膜病	慢性肺损伤	贫血	合计
研究组	30	2(6.7)	0(0)	0(0)	1(3.3)	3(10.0)
对照组	30	5(16.7)	1(3.3)	2(6.7)	3(10.0)	11(36.7)
χ²值		—	—	—	—	5.583
P值		—	—	—	—	0.016

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