Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2023, Vol. 19 ›› Issue (06): 636 -642. doi: 10.3877/cma.j.issn.1673-5250.2023.06.003

Forum

A new choice of nebulizers in aerosol inhalation therapy: vibrating mesh nebulizer

Guirong Hu1, Wei Wang2, Qiang Cai2, Liang Xie3, Hanmin Liu3,()   

  1. 1. Department of Pediatric Respiratory Immunology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, NHC Key Laboratory of Chronobiology (Sichuan University), The Joint Laboratory for Lung Development and Related Diseases of West China Second University Hospital (Sichuan University) and School of Life Sciences of Fudan University, Chengdu 610041, Sichuan Province, China; Department of Pediatrics, the Second People′s Hospital of Yibin, Yibin 644000, Sichuan Province, China
    2. Department of Pediatrics, the Second People′s Hospital of Yibin, Yibin 644000, Sichuan Province, China
    3. Department of Pediatric Respiratory Immunology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, NHC Key Laboratory of Chronobiology (Sichuan University), The Joint Laboratory for Lung Development and Related Diseases of West China Second University Hospital (Sichuan University) and School of Life Sciences of Fudan University, Chengdu 610041, Sichuan Province, China
  • Received:2023-06-22 Revised:2023-11-12 Published:2023-12-01
  • Corresponding author: Hanmin Liu
  • Supported by:
    National Natural Science Foundation of China Regional Innovation Development Joint Fund Project(U21A20333); Key Research and Development Project of Sichuan Science and Technology Department(2019YFS0037); Major Science and Technology Application Demonstration Project of Chengdu Science and Technology Bureau(2019-YF09-00087-SN)

Aerosol inhalation therapy utilizes high-speed oxygen airflow or nebulizers to transform liquid medicine into a mist, which is then inhaled through the respiratory tract to treat respiratory infections, eliminate inflammation and respiratory edema, and achieve spasm relief, sputum dilution, and help with sputum expulsion. It plays an increasingly important role in management of human respiratory system diseases. The selection of nebulizer type is crucial for clinical efficacy of aerosol therapy in children with respiratory system diseases. Currently, the nebulizers commonly used in clinical treatment for children with respiratory system diseases include ultrasonic nebulizer (UN), jet nebulizer (JN), and vibrating mesh nebulizer (VMN). Among atomizers based on different working principles, VMN has the most obvious advantages. The author intends to elaborate on the advantages and disadvantages of aerosol inhalation therapy, the advantages, disadvantages, and scope of application of UN and JN, as well as the advantages and applications of VMN, in order to provide reference for clinical selection of more suitable nebulizers for treatment of children with respiratory system diseases.

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