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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2022, Vol. 18 ›› Issue (03): 255 -261. doi: 10.3877/cma.j.issn.1673-5250.2022.03.002

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Application and research status of platelet-rich plasma in gynecological diseases

Ruijuan Xu1, Yu Lin2, Shiqiao Tan1,†()   

  1. 1Department of Obstetrics and Gynecology, Laboratory of Reproductive Endocrine and Reproductive Regulation, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    2Department of Operating Room, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2021-09-30 Revised:2022-04-30 Published:2022-06-01
  • Corresponding author: Shiqiao Tan
  • Supported by:
    Key Research Project of Science and Technology Department of Sichuan Province(2020YFS0074)
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Platelet-rich plasma (PRP) is a kind of platelet concentrate obtained from whole blood after centrifugation, with amount of growth factors and protein. PRP is widely used in orthopedics, dermatology, oral and maxillofacial surgery, plastic surgery and cosmetology, because of its functions in tissue regeneration, wound healing and scar repair, but PRP is less used in gynecology up to now. Recent studies have shown that PRP can promote growth of endometrium and folliculogenesis. Great progresses had been made in treatment of thin endometrium (TE), improvement of endometrial receptivity (ER) and restoration of ovarian function. PRP has provided new research direction and therapeutic means for many gynecological diseases. The author intends to elaborate on preparation and classification, and current status of clinical application of PRP in gynecological diseases.

Key words: Platelet-rich plasma, Platelet transfusion, Biological factors, Endometrium, Ovarian function, Endometrial receptivity, Intrauterine adhesions, Wound healing, Female
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