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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2024, Vol. 20 ›› Issue (02): 157 -165. doi: 10.3877/cma.j.issn.1673-5250.2024.02.005

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Current research status on etiology and treatment of patients with white lesions of vulva

Lin Yang1, Rutie Yin1,†()   

  1. 1. Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2023-10-30 Revised:2024-03-12 Published:2024-04-01
  • Corresponding author: Rutie Yin
  • Supported by:
    Key Research and Development Project of Department of Science and Technology of Sichuan Province(2019YFS0532); Key Research and Development Project of Chengdu(2021-YF05-01725-SN); " Two Cancers" Screening Appropriate Technology Base (Teacher Training) Project of Sichuan Health Commission(2022JDXM001)
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White lesion of vulva (WLV) is a group of local vulvar skin lesions associated with genetics, immunity, inflammation, metabolism and other factors. The malignant transformation rate of WLV is (2-25)/104. At present, the understanding of WLV in obstetrics, gynecology and dermatology academic circles at home and abroad has not yet been unified. Nearly 10% of asymptomatic WLV patients may be clinically missed or misdiagnosed. There are also great differences in treatment options. The authors will elaborate the research status of etiology and treatment of WLV, in order to provide reference for the clinical diagnosis and treatment of patients with WLV.

Key words: White lesion of vulva, Vulvar lichen sclerosus, Pruritus vulvae, Immunity, mucosal, Collagen diseases, Chemokines, Drug therapy, Physical therapy modalities, Laser therapy, Female
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