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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2021, Vol. 17 ›› Issue (04): 488 -491. doi: 10.3877/cma.j.issn.1673-5250.2021.04.017

Review

Relationship between gut microbiota and female reproductive endocrine diseases

Biyun Zhang1,1, Xiaomin Xiao2,2,†(), Xingming Zhong3,3, Zhulin Miao3,3, Leilei Li1,1, Liyan Huang1,1   

  • Received:2021-01-07 Revised:2021-06-09 Published:2021-08-01
  • Corresponding author: Xiaomin Xiao
  • Supported by:
    Natural Science Foundation of Guangdong Province(2016A030313760); Guangzhou Science and Technology Planning Project(201510010253)
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The gut microbiota, host and environment are closely related and constitute a balanced intestinal micro-ecosystem, and gut microbiota is involved in several of physiological functions of the host. The structural balance of gut microbiota plays an important role in nervous system, neuroendocrine and other systemic diseases of the host. However, in the field of reproductive endocrinology, studies on gut microbiota are still in the preliminary stage. Previous findings have shown that gut microbiota disorder is involved in the onset, development and regression of several reproductive endocrine system-related diseases. Gut microbiota disorder is associated with polycystic ovary syndrome (PCOS), endometriosis, and vaginal endoenvironment. Therefore, the regulation of gut microbiota has positive implications for the treatment of diseases related to the female reproductive endocrine system. The author intends to explore the relationship and the mechanism between gut microbiota and common reproductive endocrine diseases.

Key words: Bacterial structures, Female urogenital diseases, Polycystic ovary syndrome, Premature ovarian insufficiency, Puberty, precocious, Intestinal flora disturbance, Intestinal flora disorder, Intestinal microecosystem, Female
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