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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2021, Vol. 17 ›› Issue (04): 387 -392. doi: 10.3877/cma.j.issn.1673-5250.2021.04.003

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Current research status of diagnosis and treatment of Enterococcus faecium meningitis in children

Xiaoling Zhong, Min Shu†()   

  • Received:2021-02-03 Revised:2021-07-02 Published:2021-08-01
  • Corresponding author: Min Shu
  • Supported by:
    Science and Technology Planning Project of Science and Technology Department of Sichuan Province(2017JY0275); Program for Science & Technology and Wellbeing of Bureau of Science and Technology in Chengdu(2015-HM01-00419-SF)
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The incidence of Enterococcus faecium meningitis (EFM) in children is low, but the mortality is high. Because Enterococcus faecium has natural resistance and it is difficult for drug to penetrate cerebrospinal fluid barrier to reach effective treatment concentration, it is intractable to inhibit and kill Enterococcus faecium in children. The clinical treatment of EFM in children is difficult. In recent years, emergence of vancomycin-resistant Enterococcus faecium has made the clinical treatment for EFM more difficult. In this article, the etiology, clinical manifestations, diagnosis and treatment of EFM are briefly reviewed, in hope of deepening understanding on EFM in children and achieving better diagnosis and treatment.

Key words: Meningitis, bacterial, Enterococcus faecium, Drug resistance, microbial, Vancomycin resistance, Enterococcus faecium meningitis, Cross infection, Child
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