Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2021, Vol. 17 ›› Issue (02): 138 -141. doi: 10.3877/cma.j.issn.1673-5250.2021.02.003

Special Issue:

Forum

Current research status on pathogenesis of endometriosis

Mengshan Liang, Yaokui Zhu()   

  • Received:2021-01-09 Revised:2021-03-07 Published:2021-04-01
  • Corresponding author: Yaokui Zhu
  • Supported by:
    Natural Science Foundation of Guangdong Province(10151063201000058); Research Foundation of Medical Science and Technology of Guangdong Province(A2011344)

Endometriosis (EMS)is a benign disease with malignant behavior, and its pathogenesis has not been explained completely and clearly so far. Latest studies have found that the occurence and development of EMS can be accounted for transfer, implantation and differentiation of endometrial mesenchymal stem cells (eMSC) or bone marrow stem cells (bMSC). At the same time, inflammatory cascade reaction caused by secretion of a variety of inflammatory mediators by immune cells provides a local microenvironment for growth and invasion of endometrium ectopic tissue. In this paper, research progresses on EMS pathogenesis are summarized based on stem cells and immune cells.

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