To investigate application of enhanced recovery after surgery (ERAS) in perioperative period of minimally invasive gynecological surgery.

From February to May, 2019, a total of 151 patients who underwent minimally invasive gynecological surgery in Gynecology Center of a grade A hospital in Urumqi were selected as research subjects.They were randomly divided into study group (n=105, taking ERAS management measures in perioperative period) and control group (n=46, taking routine management measures in perioperative period) by simple randomization method.The general clinical data, disease classification and resection extent of operation, the first time to out-of-bed activity after operation, anal exhaust, drinking water and time to return to routine diet, visual analogue scale (VAS) scores on the day after surgery and in the state of rest and activity on the first day after surgery of two groups were collected. Independent-samples t test, Mann-Whitney U test or chi-square test were used for statistical comparisons. This study was approved by the Ethics Committee of the grade A hospital in Urumqi (Approval No.K202001-20). Each patient signed the informed consent for clinical research. There were no statistical significances in age, height, weight, body mass index (BMI) and other general clinical data between two groups (P>0.05).

①The proportion of malignant disease and preoperative assessment of resection extent of operation ≥ laparoscopic hysterectomy in study group were 12.4% (13/105) and 30.5% (32/105) respectively, which were significantly higher than those 0 and 15.2% (7/46) in control group, and both differences were statistically significant (χ²=6.232, 3.888; P=0.013, 0.049). ②The first time to drink water after surgery and to return to routine diet in study group were 5.0 h (3.0-9.0 h) and 17.0 h (10.0-24.0 h), respectively, which were significantly shorter than those in control group 16.0 h (13.7-19.0 h) and 24.0 h (19.5-30.2 h), and both differences were statistically significant (Z=-7.255, -4.488; P<0.001). ③VAS scores on the day after surgery and in the state of activity on the first day after surgery in study group were 3.0 scores (3.0-4.0 scores) and 2.0 scores (1.0-3.0 scores), respectively, which were significantly higher than those in control group 2.0 scores (2.0-3.0 scores) and 1.0 score (0-2.0 scores), and both the differences were statistically significant (Z=-5.458, -4.207; P<0.001). ④There were no significant differences in the length of hospital stay after surgery and the total cost of hospital stay between two groups (P>0.05).

ERAS can significantly accelerate postoperative recovery in patients undergoing minimally invasive gynecological surgery in perioperative period. Due to the relatively small sample size included in this study, and the patients in study group have more severe disease and greater scope of surgery, the application effect of ERAS in perioperative period of minimally invasive gynecological surgery still needs more large samples, multi-center, randomized controls to further studied and confirmed.