Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2019, Vol. 15 ›› Issue (05): 566 -570. doi: 10.3877/cma.j.issn.1673-5250.2019.05.014

Special Issue:

Original Article

Application of in situ morcellation of uterus myoma in laparoscopic myomectomy

Xiaolin You1, Xiaoqin Gan1,(), Liqiong Huang1, Jiajia Zhang1, Qiang Zhang1, Lu Huang1, Wei Yuan1, Juan Li1   

  1. 1. Department of Obstetrics and Gynecology, Chengdu Women′s and Children′s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan Province, China
  • Received:2019-03-06 Revised:2019-09-10 Published:2019-10-01
  • Corresponding author: Xiaoqin Gan
  • About author:
    Corresponding author: Gan Xiaoqin, Email:
  • Supported by:
    Scientific Research Project of Sichuan Health and Family Planning Commission(18PJ056)
Objective

To explore the value of uterus myoma (UM) treatment by in situ morcellation of UM in laparoscopic myomectomy (LM).

Methods

A total of 72 patients who were diagnosed as UM and received LM treatment in Chengdu Women′s and Children′s Central Hospital between June 2014 and June 2018 were randomly selected as research subjects by random envelope method. By random number table method, the patients were randomly divided into study group (n=36, treatment UM by in situ morcellation of UM in LM) and control group (n=36, stripping UM first and then morcellation of UM in LM). The operation duration time, volume of intraoperative blood loss, postoperative vent time, and length of hospital stays were compared between two groups by independent-samples t test. The procedures followed in this study were in accordance with the standards established by the Ethics Committee of the Chengdu Women′s and Children′s Central Hospital, and this study was approved by this committee (approval date: April 14 of 2014). Clinical research informed consent was obtained and signed from each patient.

Results

①There were no statistically significant differences between two groups in the general clinical data, such as maximum diameter of UM, and the age, body mass index (BMI), and proportions of history of abdominal surgery, multipara, number of UM ≥2 of patients (P>0.05). ②The operation duration time in study group was (42.4±5.5) min, which was statistically shorter than that of (78.6±6.0) min in control group, and volume of intraoperative blood loss in study group was (20.5±4.2) mL, which was significantly lower than that of (48.2±5.1) mL in control group, and both the differences were statistically significant (t=3.762, 3.523; P=0.001, 0.012). There were no significant differences between two groups in the postoperative vent time and length of hospital stays (P>0.05). There were no surgically related complications in both groups.

Conclusions

Applying in situ morcellation of UM in LM in treatment of UM patients is an efficient way to further reduce operative duration time and the volume of intraoperative blood loss. Because the sample size of this study is relatively small, whether this method is worthy of clinical promotion and application still needs to beconfirmed by multi-center, large-sample size, and randomized controlled trials.

表1 2组UM患者一般临床资料比较
表2 2组UM患者术中及术后情况比较(±s)
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