Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2017, Vol. 13 ›› Issue (03): 270 -275. doi: 10.3877/cma.j.issn.1673-5250.2017.03.005

Special Issue:

Editorial

Anesthesia management of patients undergoing ovarian tumor excision with anti N-methyl-D-aspartate receptor encephalitis

Xingrong Gao1, Dong Luo1,()   

  1. 1. Department of Anesthesiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Chengdu 610041, Sichuan Province, China
  • Received:2017-03-01 Revised:2017-05-11 Published:2017-06-01
  • Corresponding author: Dong Luo
  • About author:
    Corresponding author: Luo Dong, Email:

Anti N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune encephalitis. Its clinical symptoms include psychiatric disorders, seizure disorders, autonomic instability, central hypoventilation and so on. Anti NMDA receptor encephalitis patients need respiratory support. This disease is directly associated with the immunoglobulin (Ig) G antibodies against NMDA receptor NR1 subunit. Anti NMDA receptor encephalitis is commonly associated with ovarian teratomas and typically occurs in young women. The removal of ovarian teratomas combined with immunotherapy, is always associated with a good prognosis. It is still not consistent on the ideal anesthesia method for this kind of patients undergoing ovarian tumor excision. We review the anesthesia management of patients with anti NMDA receptor encephalitis undergoing ovarian teratoma excision in order to provide references for such patients.

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