Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2012, Vol. 08 ›› Issue (04): 515 -518. doi: 10.3877/cma.j.issn.1673-5250.2012.04.036

Special Issue:

Review

Immune Function Changes of Children With Hand-Foot-Mouth Disease Caused by Enterovirus 71 Infection and Its Clinical Significance

De-hong SUN1, Yong-feng YU1, Gui-juan ZHAO1, Ding-rong ZHANG1, Shu-zhen XU1()   

  1. 1. People's Hospital of Jimo City, Jimo 266200, Shandong Province, China
  • Received:2012-02-05 Revised:2012-05-27 Published:2012-08-01
  • Corresponding author: Shu-zhen XU
  • About author:
    (Corresponding author: XU Shu-zhen, Email: )

Children with hand-foot-mouth disease (HFMD) which caused by enterovirus 71 (EV71) can appear central nervous and respiratory system damage. Meanwhile, EV71 can cause encephalitis, brain edema and myocarditis. Some severe cases are prone to death. The pathogenesis of HFMD is likely related to immune disorders caused by EV71 infection. Additional, systemic inflammatory response syndrome (SIRS) may play an important role in attack. As a result, it is necessary for us to take cellular immune support treatment in time and block SIRS development. It is also significant for children with HFMD to improve the prognosis.

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