Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2010, Vol. 06 ›› Issue (03): 192 -194. doi: 10.3877/cma.j.issn.1673-5250.2010.03.014

Original Article

Effects of Artificial Defecation on the Feeding Intolerance and Level of Serum Gastrin in Premature Infants

Hong-yan SUN, Wen-bin DONG, Lian-yu ZHANG, An-fang XIONG, You-ying LU   

  1. Department of Nursing and Hygiene, Luzhou Medical College, Luzhou 646000, Sichuan Province, China
  • Published:2010-06-01
Objective

To study effects of artificial defecation on the feeding intolerance of and serum gastrin level in premature infants.

Methods

From April 2008 to February 2009, 30 premature infants with feeding intolerance who were admitted to the Department of Newborn, Affiliated Hospital of Luzhou Medical College and received nasal feeding of milk powder were enrolled in this study. They were randomly divided into artificial defecation group (n=15) and control group (n=15). The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Affiliated Hospital of Luzhou Medical College. Informed consent was obtained from the parents of each participating neonate. Serum gastrin levels were measured by radio immunoassay, and the occurrence of feeding intolerance were investigated in both groups.

Results

The occurrence of feeding intolerance of artificial defecation group was lower than that of control group (26.67% vs. 66.67%), the time of recovering to their birth weight and reaching the whole stomach intestine feeding were significantly decreased in artificial defecation group[(10.21±2.81) d vs. (16.59±3.37) d, (9.39±3.62) d vs. (14.17±2.54)d] (P<0.05). The serum gastrin levels in artificial defecation were significantly higher than those of control group.

Conclusion

The artificial defecation could increase gastrin secretion and decrease the occurrence of feeding intolerance.

1 Niu SL, Zhang YM.Effects of non-nutritive sucking on the intolerance of eternal feeding and serum gastrin in premature infants[J].Chin J Mod Drug Appl, 2008, 2(17): 1787-1788.[牛世平,张玉梅.非营养性吸吮对早产儿喂养不耐受及血清胃泌素影响的研究[J].中国现代药物应用,2008, 2(17): 1787-1788.]
2 Bombell S, McGuire W. Early trophic feeding for very low birth weight infants[J]. Cochrane Database Syst Rev, 2009, 8 (3): CD000504.
3 Indrio F, Riezzo G, Raimondi F, et al. The effects of probiotics on feeding tolerance, bowel habits, and gastrointestinal motility in preterm newborns[J]. J Pediatr, 2008, 152(6): 801-806.
4 Sun M.Research of Preterm children parenteral nutrition associated cholestasis[J/CD].Chin J Obstet Gynecol Pediatr (Electron Ed), 2008, 4(6):397-401.[孙梅.早产儿胃肠外营养相关性胆汁淤积的研究进展[J/CD].中华妇幼临床医学杂志:电子版,2008, 4(6):397-401.]
5 Jiang H, Wang YM, Yu FY.Effectiveness of early artificial defecation in low birth weight infants[J].J Nurs Sci, 2008, 23(7): 30-31.[姜红,王一呜,于凤英.低出生体重儿早期人工通便效果观察[J].护理学杂志,2008, 23(7): 30-31.]
6 Wang J, Chen XX, Wang L, et al.Gastrointestinal function and the levels of gastrin and motilin in premature infants[J].J Guiyang Med Coll, 2007, 32(4): 378-381.[王鉴,陈晓霞,王莉,等.早产儿胃肠功能与胃泌素、胃动素的相关性研究[J].贵阳医学院学报,2007, 32(4): 378-381.]
7 Gounaris A, Costalos C, Varchalama E, et al. Gastric emptying of preterm neonates receiving domperidone[J]. Neonatology, 2010, 97(1): 56-60.
8 Indrio F, Riezzo G, Raimondi F, et al. Effects of probiotic and prebiotic on gastrointestinal motility in newborns[J]. J Physiol Pharmacol, 2009, 60(Suppl 6): 27-31.
9 Ameh N, Ameh EA. Timing of passage of first meconium and stooling pattern in normal Nigerian newborns[J]. Ann Trop Paediatr, 2009, 29(2): 129-133.
10 Bekkali N, Hamers SL, Schipperus MR, et al. Duration of meconium passage in preterm and term infants[J]. Arch Dis Child Fetal Neonatal Ed, 2008, 93(5): F376-379.
11 Ng PC. Use of oral erythromycin for the treatment of gastrointestinal dysmotility in preterm infants[J]. Neonatology, 2009, 95(2): 97-104.
12 Chawla D, Thukral A, Agarwal R, et al. Parenteral nutrition[J]. Indian J Pediatr, 2008, 5(4): 377-383.
13 Ben XM. Nutritional management of newborn infants: Practical guidelines[J]. World J Gastroenterol, 2008, 14(40): 6133-6139.
14 Yang CK.Effects of touching on the intolerance of eternal feeding and serum gastrin in premature infants[J].Mod J Integrated Traditional Chin West Med, 2008, 17(26): 4082-4083.[杨长坤.新生儿抚触对早产儿喂养不耐受及血清胃泌素影响的研究[J].现代中西医结合杂志,2008, 17(26): 4082-4083.]
15 Im H, Kim E. Effect of yakson and gentle human touch versus usual care on urine stress hormones and behaviors in preterm infants: A quasi-experimental study[J]. Int J Nurs Stud, 2009, 46(4): 450-458.
16 Modrcin-Talbott MA, Harrison LL, Groer MW, et al. The biobehavioral effects of gentle human touch on preterm infants[J]. Nurs Sci Quarterly, 2003, 16(1): 60-67.
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