Effects of double-lumen water balloon combined with oxytocin on cervical ripening and impact on pregnancy outcomes in term pregnant women with borderline oligohydramnios

doi:10.3877/cma.j.issn.1673-5250.2025.06.010

Objective

To explore the effects of the double-lumen water balloon combined with oxytocin on cervical ripening and impact on pregnancy outcomes in term pregnant women with borderline oligohydramnios.

Methods

A total of 88 term borderline oligohydramnios pregnant women who delivered at the Chaohu Hospital Affiliated to Anhui Medical University between March 2021 and March 2024 were selected as the study subjects. They were randomly divided using a random number table method into study group (n=44, inducing labor with double-lumen water balloon combined with oxytocin) and control group (n=44, inducing labor with oxytocin). The cervical ripeness before and after induced labor, induction outcomes, neonatal outcomes, and adverse pregnancy outcomes were compared between two groups using the independent-samples t test or chi-square test, as appropriate. This study was approved by the Medical Ethics Committee of Chaohu Hospital Affiliated to Anhui Medical University (Approval No. KYXM202103-053). There were no significant differences in baseline characteristics, including maternal age, gestational age, and gravidity between the two groups (P> 0.05).

Results

①After labor induction, the scores of cervical position, cervical consistency, cervical dilation, cervical effacement, and fetal station and the total Bishop score were all significantly better in the study group than those in control group (t=11.58, 9.51, 11.03, 11.07, 9.98, 6.24; all P<0.001). The proportion of vaginal delivery in study group was 93.2% (41/44), which was significantly higher than that in control group (77.3%, 34/44) (χ²=5.57, P=0.018). The induction bleeding volume and postpartum blood loss in study group were significantly lower than those in control group, and the durations of the first and third stages of labor were significantly shorter in the study group (t=2.37, P=0.020; t=2.85, P=0.005; t=3.23, P=0.002; t=8.80, P<0.001). ②There were no significant differences between two groups in neonatal birth weight and Apgar score at 5 min after delivery (P>0.05). ③The overall incidence of adverse pregnancy outcomes was significantly lower in study group than that in control group [2.3% (1/44) vs 13.6% (6/44), χ²=3.88, P=0.049].

Conclusions

The combination of a double-lumen water balloon with oxytocin has certain value in promoting cervical ripening and increasing vaginal delivery rates in full-term pregnant women with borderline oligohydramnios.

Key words: Term birth, Borderline oligohydramnios, Dual balloon catheter, Oxytocin, Cervical ripening, Labor, induced, Pregnant women

表1 2组孕妇一般临床资料比较(

±s)

组别	例数	年龄(岁)	孕龄(周)	孕次(次)
研究组	44	30.2±3.2	38.9±1.3	1.57±0.29
对照组	44	30.8±3.6	38.5±1.3	1.61±0.30
t值		0.90	1.34	0.64
P值		0.368	0.182	0.527

表1 2组孕妇一般临床资料比较(

±s)

组别	例数	年龄(岁)	孕龄(周)	孕次(次)
研究组	44	30.2±3.2	38.9±1.3	1.57±0.29
对照组	44	30.8±3.6	38.5±1.3	1.61±0.30
t值		0.90	1.34	0.64
P值		0.368	0.182	0.527

表2 2组孕妇诱发临产前、后宫颈成熟度Bishop评分比较(分，

±s)

组别	例数	宫颈位置		宫颈软硬度		宫颈扩张程度
组别	例数	诱发临产前	诱发临产后	诱发临产前	诱发临产后	诱发临产前	诱发临产后
研究组	44	0.55±0.15	1.54±0.23	0.50±0.15	1.52±0.25	0.62±0.12	1.79±0.26
对照组	44	0.56±0.12	1.03±0.18	0.48±0.13	1.07±0.19	0.65±0.15	1.13±0.30
t值		0.34	11.58	0.67	9.51	1.04	11.03
P值		0.731	<0.001	0.506	<0.001	0.303	<0.001
组别	例数	宫颈管消退程度		胎头位置		总分
组别	例数	诱发临产前	诱发临产后	诱发临产前	诱发临产后	诱发临产前	诱发临产后
研究组	44	0.75±0.15	1.75±0.23	0.67±0.14	1.72±0.24	3.10±1.05	7.96±1.29
对照组	44	0.78±0.17	1.23±0.21	0.68±0.13	1.13±0.31	3.15±1.02	6.25±1.28
t值		0.88	11.07	0.35	9.98	0.23	6.24
P值		0.383	<0.001	0.729	<0.001	0.821	<0.001

表2 2组孕妇诱发临产前、后宫颈成熟度Bishop评分比较(分，

±s)

组别	例数	宫颈位置		宫颈软硬度		宫颈扩张程度
组别	例数	诱发临产前	诱发临产后	诱发临产前	诱发临产后	诱发临产前	诱发临产后
研究组	44	0.55±0.15	1.54±0.23	0.50±0.15	1.52±0.25	0.62±0.12	1.79±0.26
对照组	44	0.56±0.12	1.03±0.18	0.48±0.13	1.07±0.19	0.65±0.15	1.13±0.30
t值		0.34	11.58	0.67	9.51	1.04	11.03
P值		0.731	<0.001	0.506	<0.001	0.303	<0.001
组别	例数	宫颈管消退程度		胎头位置		总分
组别	例数	诱发临产前	诱发临产后	诱发临产前	诱发临产后	诱发临产前	诱发临产后
研究组	44	0.75±0.15	1.75±0.23	0.67±0.14	1.72±0.24	3.10±1.05	7.96±1.29
对照组	44	0.78±0.17	1.23±0.21	0.68±0.13	1.13±0.31	3.15±1.02	6.25±1.28
t值		0.88	11.07	0.35	9.98	0.23	6.24
P值		0.383	<0.001	0.729	<0.001	0.821	<0.001

表3 2组孕妇妊娠结局比较

组别	例数	分娩方式[例数(%)]		诱发临产中出血量(mL，±s)	产后出血量(mL，±s)
组别	例数	自然分娩	剖宫产术分娩	诱发临产中出血量(mL，±s)	产后出血量(mL，±s)
研究组	44	41(93.2)	3(6.8)	95.8±17.4	127.4±21.7
对照组	44	34(77.3)	10(22.7)	104.9±18.8	140.1±19.9
统计量		χ²＝5.57		t＝2.37	t＝2.85
P值		0.018		0.020	0.005
组别	例数	第1产程持续时间(h，±s)^a	第2产程持续时间[h，M(Q₁，Q₃)]^a	第3产程持续时间(min，±s)^a
研究组	44	12.1±2.7	1.4(0.9，2.1)	6.3±1.0
对照组	44	14.2±3.1	1.1(0.8，1.9)	8.8±1.5
统计量		t＝3.23	Z＝1.51	t＝8.80
P值		0.002	0.131	<0.001

表3 2组孕妇妊娠结局比较

组别	例数	分娩方式[例数(%)]		诱发临产中出血量(mL，±s)	产后出血量(mL，±s)
组别	例数	自然分娩	剖宫产术分娩	诱发临产中出血量(mL，±s)	产后出血量(mL，±s)
研究组	44	41(93.2)	3(6.8)	95.8±17.4	127.4±21.7
对照组	44	34(77.3)	10(22.7)	104.9±18.8	140.1±19.9
统计量		χ²＝5.57		t＝2.37	t＝2.85
P值		0.018		0.020	0.005
组别	例数	第1产程持续时间(h，±s)^a	第2产程持续时间[h，M(Q₁，Q₃)]^a	第3产程持续时间(min，±s)^a
研究组	44	12.1±2.7	1.4(0.9，2.1)	6.3±1.0
对照组	44	14.2±3.1	1.1(0.8，1.9)	8.8±1.5
统计量		t＝3.23	Z＝1.51	t＝8.80
P值		0.002	0.131	<0.001

表4 2组孕妇分娩新生儿的出生体重与生后5 min Apgar评分比较(

±s)

组别	例数	出生体重(kg)	生后5 min Apgar评分(分)
研究组	44	3.8±0.5	8.8±0.6
对照组	44	3.9±0.4	8.5±0.6
t值		1.25	1.84
P值		0.215	0.069

表4 2组孕妇分娩新生儿的出生体重与生后5 min Apgar评分比较(

±s)

组别	例数	出生体重(kg)	生后5 min Apgar评分(分)
研究组	44	3.8±0.5	8.8±0.6
对照组	44	3.9±0.4	8.5±0.6
t值		1.25	1.84
P值		0.215	0.069

表5 2组孕妇不良妊娠结局总体发生率比较[例数(%)]

组别	例数	胎儿宫内窘迫	羊水粪染	新生儿窒息	宫颈裂伤	总体发生率
研究组	44	1(2.3)	0(0)	0(0)	0(0)	1(2.3)
对照组	44	2(4.5)	2(4.5)	1(2.3)	1(2.3)	6(13.6)
χ²值		—	—	—	—	3.88
P值		—	—	—	—	0.049

表5 2组孕妇不良妊娠结局总体发生率比较[例数(%)]

组别	例数	胎儿宫内窘迫	羊水粪染	新生儿窒息	宫颈裂伤	总体发生率
研究组	44	1(2.3)	0(0)	0(0)	0(0)	1(2.3)
对照组	44	2(4.5)	2(4.5)	1(2.3)	1(2.3)	6(13.6)
χ²值		—	—	—	—	3.88
P值		—	—	—	—	0.049

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