Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2017, Vol. 13 ›› Issue (04): 461 -465. doi: 10.3877/cma.j.issn.1673-5250.2017.04.016

Special Issue:

Original Article

Analysis of clinical characteristics of small for gestational age infants and appropriate for gestational age infants among late preterm infants

Yang He1, Limei Cai2, Jun Tang1,(), Hua Wang1, Dezhi Mu1   

  1. 1. Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    2. Department of Neonatology, Qingbaijiang Women and Children Health Hospital of Chengdu, Chengdu 610300, Sichuan Province, China
  • Received:2017-05-17 Revised:2017-07-08 Published:2017-08-01
  • Corresponding author: Jun Tang
  • About author:
    Corresponding author: Tang Jun, Email:
Objective

To explore the clinical characteristics of small for gestational age (SGA) infants and appropriate for gestational age (AGA) infants among late preterm infants, and to provide a clinical basis for improving the management quality of premature infants during the perinatal period.

Methods

From November 2014 to November 2015, a total of 688 late preterm infants who were discharged from Department of Neonatology, West China Second University Hospital, Sichuan University, were chosen as study subjects. According to gestational age and birth weight, 151 SGA preterm infants were included in SGA group, 537 AGA preterm infants were included in AGA group. The clinical medical records of preterm infants were analyzed retrospectively. The general clinical data, common complications and maternal pregnancy complications between two groups of preterm infants were compared statistically.

Results

①The birth weight of SGA group was lower than that of AGA group, and the duration of hospital stay was longer than that of AGA group, and the differences were statistically significant(P<0.05). There were also significant differences between two groups of preterm infants in constituent ratio of gender and delivery modes (cesarean section or eutocia) (P<0.05). ②The incidence rate of respiratory distress syndrome (RDS) of SGA group was lower than that of AGA group, while the incidence rates of alimentary tract hemorrhage, necrotizing enterocolitis (NEC) and hypoglycemia were higher than those of AGA group, and the differences were were statistically significant (P<0.05). ③The incidence rates of hypertensive disorder complicating pregnancy, multiple pregnancy and eclampsia of SGA group of maternal were higher than those of AGA group, while the incidence rate of premature rupture of fetal membranes was lower than that of AGA group, and the differences were statistically significant (P<0.05). ④For caesarean section delivery, there were no significant differences between mothers using and without using glucocorticoids before childbirth in the incidence rates of RDS for both SGA and AGA preterm infants.

Conclusions

There were more perinatal complications and longer length of stays of SGA preterm infants than AGA preterm infants. Therefore, the management and follow-up of SGA among late preterm infants should be strengthened to improve their quality of life.

表1 2组早产儿一般临床资料比较
表2 2组早产儿并发症发生率比较[例数(%)]
表3 2组早产儿的母亲孕期并发症发生情况比较[例数(%)]
表4 剖宫产母亲产前使用与未使用糖皮质激素的早产儿RDS发生率比较[例数(%)]
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