Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2012, Vol. 08 ›› Issue (05): 650 -653. doi: 10.3877/cma.j.issn.1673-5250.2012.05.033

Special Issue:

Review

Application Progress of Epigenetic in Noninvasive Prenatal Diagnosis

Hao ZHOU1, Ping YI1(), Li LI1   

  1. 1. Department of Gynecology and Obstetrics, Third Military Medical University Daping Hospital, Research Institute of Field Surgery, Chongqing 400042, China
  • Received:2012-06-10 Revised:2012-09-01 Published:2012-10-01
  • Corresponding author: Ping YI
  • About author:
    (Corresponding author: YI Ping, Email: )

Fetal epigenetic markers can be used as qualitative markers to indicate the presence of fetal DNA or as quantitative markers to quantify the amount of fetal DNA. It also can be used for the prenatal detection of fetal trisomy. Many fetal epigenetic markers have been discovered, and some of them have been applied in the clinical setting. However, large numbers of noninvasive prenatal diagnostic tests must be done in the future.

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