Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2010, Vol. 06 ›› Issue (04): 290 -295. doi: 10.3877/cma.j.issn.1673-5250.2010.04.023

Evidence and Clinical Application of Drug Treatment on Bronchopulmonary Dysplasia

Hua WANG   

  1. West China Second University Hospital, Sichuan University, Chengdu 610041, China
  • Published:2010-08-01

Bronchopulmonary dysplasia (BPD) is one of the most challenging complications in premature infants. The incidence of bronchopulmonary dysplasia has been increasing over the past two decades in parallel with an improvement in the survival of this population. Furthermore, clinical characteristics of preterm infants affected by bronchopulmonary dysplasia have changed considerably, and the newer definition to clarify the term of bronchopulmonary dysplasia have also evolved since its first description more than four decades ago. Several drug therapies have also evolved, either to manage these infants' respiratory distress syndrome(RDS) with an aim to prevent bronchopulmonary dysplasia or to manage the established condition. Although there is good evidence to support the 'routine' use of some therapies, many other therapies currently used in relation to bronchopulmonary dysplasia remain on experiences that we have adopted. In this article, we discuss the support for the drug therapies used in relation to bronchopulmonary dysplasia, so as to provide bases for the clinical use of these drugs.

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