Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2009, Vol. 05 ›› Issue (04): 389 -392. doi: 10.3877/cma.j.issn.1673-5250.2009.04.114

Original Article

Clinical Study on Bispectral Index Monitoring Used in Out-Patients Undewent Artifical Abortion

Hai-bing LI, Shou-jing ZHOU, Zhi-qiang LIU, Yi-bing YU, Xiu-bin CHEN   

  1. Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai 200032, China
  • Published:2009-08-01
Objective

To evaluate the process and significance of bispectral index(BIS) monitoring in out-patients who underwent artificial abortion under propofol-sufentanil anesthesia.

Methods

From June to October 2008, 180 patients who were underwent selective artificial abortion under propofol-sufentanil anesthesia were randomly divided into regular monitoring+ BIS monitoring group (group Ⅰ, n=90) and regular clinical monitoring group (group Ⅱ, n=90). Informed consent was obtained from all participates. In group Ⅰ, the maintenance dose of propofol infusion were adjusted to achieve a target bispectral index of 40~55. In group Ⅱ, propofol dose adjustments were made based only on standard clinical signs. The mean airway pressure (MAP), heart rate (HR), pulse oxygen saturation (SpO2) and bispectral index were detected at T0 (at giving drug), T1(loss of eyelash reflex), T2(cervical dilatation), T3(dilatation and curettage), T4(withdrawl vaginal speculum), T5(at analepsia) of two groups. The dosage of propofol, intraoperative response, duration of operation and recovery parameters were recorded.

Results

There were no significant differences between two groups of general clinical information, mean airway pressure before anaesthesia, heart rate, pulse oxygen saturation, and bispectral index monitoring (P>0.05). The dosage of propofol and duration of postoperative stay in hospital were significantly less and shorter in group Ⅰ than those of group Ⅱ(P<0.01), so did the decrease of mean airway pressure at T1 and T2 (P<0.01). And there also had significant difference of incidence of adverse reactions between two groups(P<0.01).

Conclusion

Titrating propofol with bispectral index monitoring during intravenous anesthesia for artifical abortion in chinic could prevent propofol under or over dose, decrease the change of haemodynamics, avoid limb movement, keep hemodynamics stable and make recovery quicker.

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