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中华妇幼临床医学杂志(电子版) ›› 2019, Vol. 15 ›› Issue (04) : 468 -471. doi: 10.3877/cma.j.issn.1673-5250.2019.04.019

所属专题: 文献

综述

川崎病体外研究现状
郑小兰1, 吴刚1,(), 张怡1, 华益民1, 周开宇1   
  1. 1. 四川大学华西第二医院儿科、出生缺陷与相关妇儿疾病教育部重点实验室,成都 610041
  • 收稿日期:2019-03-09 修回日期:2019-07-01 出版日期:2019-08-01
  • 通信作者: 吴刚

In vitro study status of Kawasaki disease

Xiaolan Zheng1, Gang Wu1,(), Yi Zhang1, Yimin Hua1, Kaiyu Zhou1   

  1. 1. Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2019-03-09 Revised:2019-07-01 Published:2019-08-01
  • Corresponding author: Gang Wu
  • About author:
    Corresponding author: Wu Gang, Email:
  • Supported by:
    National Natural Science Foundation of China(81571515); Science and Technology Program for Wellbeing of Chengdu Science and Technology Bureau(2015-HM01-00456-SF)
引用本文:

郑小兰, 吴刚, 张怡, 华益民, 周开宇. 川崎病体外研究现状[J/OL]. 中华妇幼临床医学杂志(电子版), 2019, 15(04): 468-471.

Xiaolan Zheng, Gang Wu, Yi Zhang, Yimin Hua, Kaiyu Zhou. In vitro study status of Kawasaki disease[J/OL]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2019, 15(04): 468-471.

川崎病(Kawasaki disease)是一种主要发生在5岁以下婴幼儿的全身中小动脉血管炎,是发达国家儿童获得性心脏病的最常见病因。临床对于川崎病的发病机制迄今尚未阐明。随着近年分子生物学技术的发展,对川崎病的研究取得很大进步。笔者拟从基因组学、蛋白质组学、外泌体3个方面,对川崎病的体外研究现状进行阐述。

Kawasaki disease is a systemic vasculitis mainly occurs in the middle and small arteries in children under five years old. It has been proved to be the main causation of acquired heart diseases of children in developed countries. The pathogenesis of Kawasaki disease is still unknown, but great progresses have been made in vitro studies of Kawasaki disease with the rapid development of molecular biotechnology in recent years. This article focuses on in vitro research status of Kawasaki disease including genomics, proteomics and exosomes.

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