切换至 "中华医学电子期刊资源库"

中华妇幼临床医学杂志(电子版) ›› 2017, Vol. 13 ›› Issue (04) : 466 -469. doi: 10.3877/cma.j.issn.1673-5250.2017.04.017

所属专题: 文献

论著

新疆维吾尔自治区乌鲁木齐市维吾尔族和汉族育龄期妇女碘营养状况调查分析
郭艳英1, 阿地拉·阿里木1, 辛亮1, 李素丽1, 赵红丽1, 热孜万古丽·乌斯曼1, 王新玲1,()   
  1. 1. 830001 乌鲁木齐,新疆维吾尔自治区人民医院内分泌科
  • 收稿日期:2017-04-18 修回日期:2017-07-10 出版日期:2017-08-01
  • 通信作者: 王新玲

Investigation and analysis of iodine nutritional status in Han and Uygur nationalities in childbearing age women in Urumqi, Xinjiang Uygur Autonomous Region

Yanying Guo1, Adila Alimu1, Liang Xin1, Suli Li1, Hongli Zhao1, Reziwanguli Wusiman1, Xinling Wang1,()   

  1. 1. Department of Endocrinology, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China
  • Received:2017-04-18 Revised:2017-07-10 Published:2017-08-01
  • Corresponding author: Xinling Wang
  • About author:
    Corresponding author: Wang Xinling, Email:
引用本文:

郭艳英, 阿地拉·阿里木, 辛亮, 李素丽, 赵红丽, 热孜万古丽·乌斯曼, 王新玲. 新疆维吾尔自治区乌鲁木齐市维吾尔族和汉族育龄期妇女碘营养状况调查分析[J]. 中华妇幼临床医学杂志(电子版), 2017, 13(04): 466-469.

Yanying Guo, Adila Alimu, Liang Xin, Suli Li, Hongli Zhao, Reziwanguli Wusiman, Xinling Wang. Investigation and analysis of iodine nutritional status in Han and Uygur nationalities in childbearing age women in Urumqi, Xinjiang Uygur Autonomous Region[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2017, 13(04): 466-469.

目的

了解新疆维吾尔自治区乌鲁木齐市某社区维吾尔族和汉族育龄期妇女碘营养水平及其差异。

方法

选取2013年5月在乌鲁木齐某社区进行甲状腺疾病流行病学调查的2 080例受试者中,资料完整的585例女性受试者为研究对象,年龄为18~45岁。按照不同民族,将其分为维吾尔族组(n=326)与汉族组(n=259)。回顾性分析2组受试者人体质量指数(BMI)、颈围、腹围、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TgAb)、甲状腺过氧化物酶抗体(TPOAb)水平等一般临床资料,采用尿中碘的砷铈催化分光光度法检测尿碘水平。本研究遵循的程序符合新疆维吾尔自治区人民医院伦理委员会制定的伦理学标准,得到该委员会批准,并与受试者签署临床研究知情同意书。

结果

①维吾尔族组受试者BMI和腹围,均大于汉族组受试者,2组比较,差异均有统计学意义(t=7.015、7.104,P<0.001)。维吾尔族组和汉族组受试者的年龄、颈围及TSH、TgAb和TPOAb水平比较,差异均无统计学意义(P>0.05)。②维吾尔族组、汉族组受试者尿碘水平中位数分别为133.8 μg/L (34.1~568.2 μg/L)和131.7 μg/L (27.7~513.6 μg/L),二者比较,差异无统计学意义(Z=-0.156,P=0.876)。维吾尔族组、汉族组受试者碘缺乏、碘适量、碘超足量及碘过量构成比比较,差异无统计学意义(χ2=1.556,P=0.669)。

结论

新疆维吾尔自治区乌鲁木齐市某社区维吾尔族、汉族育龄期部分妇女存在碘缺乏,维吾尔族和汉族育龄期妇女碘营养状况无明显差异。

Objective

To investigate the urinary iodine levels and differences between Han and Uygur nationalities in childbearing age women in Urumqi, Xinjiang Uygur Autonomous Region.

Methods

In May 2013, a total of 585 subjects who received epidemiological survey of thyroid disorders with complete clinical data in a community of Urumqi were chosen as research subjects. According to different nationalities, they were divided into Uygur group (n=326) and Han group (n=259). Body mass index (BMI), neck circumference, waist circumference, thyroid-stimulating hormone (TSH), thyroglobulin antibody (TgAb), and thyroid peroxidase antibody (TPOAb) levels were retrospectively analyzed. The levels of urinary iodine were determined by As3+ -Ce4+ catalytic spectrophotometry. This study has been approved by the ethic committee board of People′s Hospital of Xinjiang Uygur Autonomous Region.

Results

①BMI and waist circumference in Uygur group were higher than those of Han group, and the differences were statistically significant (t=7.015, 7.104; P<0.001). However, there were no significant differences between two groups in the aspects of age, neck circumference, TSH, TgAb and TPOAb levels (P>0.05). ②The median urinary iodine levels of Uygur group and Han group were 133.8 μg/L(34.1-568.2 μg/L) and 131.7 μg/L (27.7-513.6 μg/L), respectively, which showed no significant difference (Z=-0.156, P=0.876). Furthermore, there was no statistical difference between Uygur group and Han group among iodine deficiency (32.8% vs 31.3%), iodine sufficient (43.2% vs 45.2%), iodine super-sufficient (12.6% vs 14.7%), and iodine excess (11.4% vs 8.9%) (χ2=1.556, P=0.669) .

Conclusions

Part of both Uygur and Han nationality women during their childbearing age in a community in Urumqi are suffering from iodine deficiency. And there is no statistically significant difference between them in iodine nutritional status.

表1 2组受试者一般临床资料比较
表2 2组受试者尿碘水平及不同尿碘水平构成比比较
[1]
中国营养学会膳食指南修订专家委员会妇幼人群膳食指南修订专家工作组. 备孕妇女膳食指南[J]. 中华围产医学杂志,2016, 19(8): 561-564.
[2]
Bath SC, Steer CD, Golding J, et al. Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon longitudinal study of parents and children (ALSPAC) [J]. Lancet, 2013, 382(9889): 331-337.
[3]
王锋锐,张玲,艾亥特·艾萨,等. 1995-2011年新疆碘缺乏病防治效果分析与病情预测[J]. 中华地方病学杂志,2014, 33(3): 351-351.
[4]
中华人民共和国卫生部. WS/T 107-2006尿中碘的砷铈催化分光光度测定方法 [S].北京:人民卫生出版社,2006.
[5]
World Health Organization,Department of Nutrition for Health and Development, International Council for Control of Iodine Deficiency Disorders, UNICEF. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programe managers. 2nd ed [EB/OL]. (2017-02-18) [2017-06-30].

URL    
[6]
李桂娟,林彩莲. 妊娠母体甲状腺功能减退与母婴妊娠结局的相关性分析[J]. 中国妇幼健康研究,2016, 27(5): 643-646.
[7]
Obican SG, Jahnke GD, Soldin OP, et al. Teratology public affairs committee position paper: iodine deficiency in pregnancy[J]. Birth Defects Res A Clin Mol Teratol, 2012, 94(9): 677-682.
[8]
于海华,宫建,于嵩,等. 不同碘营养状态对晚孕期孕妇心电图的影响[J/CD]. 中华妇幼临床医学杂志(电子版),2015,11(6): 685-688.
[9]
孙明强,周玉兰,延永,等. 新生儿外周血促甲状腺激素升高与母亲甲状腺功能关系的研究[J]. 中华妇幼临床医学杂志(电子版),2010,6(4): 255-258.
[10]
Zhang F, Wen Y, Guo X, et al. Genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in Han Chinese [J]. Arthritis Rheumatol, 2015, 67(1): 176-181.
[11]
胡边,蒋继勇,杨自更,等. 新疆育龄妇女和儿童碘营养水平分析[J]. 上海预防医学,2005, 17(12): 607-608.
[12]
乔富宇,刘建山,张震,等. 北京市西城区妊娠妇女与育龄妇女碘营养状况分析[J]. 临床和实验医学杂志,2013, 12(17): 1357.
[13]
黄文彩,邓黎,陈载鑫,等. 东莞厚街地区育龄妇女碘营养状况及妊娠中期甲状腺激素参考值的探讨[J]. 国际检验医学杂志,2017, 38(2): 160-162.
[14]
王新玲,艾合买提江·吐呼提,马福慧,等. 新疆乌鲁木齐市健康成年人碘营养状况调查分析[J]. 中华健康管理学杂志,2015, 9(4): 297-300.
[15]
Korevaar TI. Evidence-based tightrope walking: the 2017 guidelines of the american thyroid association for the diagnosis and management of thyroid disease during pregnancy and the postpartum [J]. Thyroid, 2017, 27(3): 309-311.
[16]
Hanson MA, Bardsley A, De-Regil LM, et al. 国际妇产科联盟关于青少年、孕前及孕期女性的营养建议(一) [J]. 中华围产医学杂志,2016, 19(12): 960-963.
[17]
Teng W, Shan Z, Teng X, et al. Effect of iodine intake on thyroid diseases in China [J]. N Engl J Med, 2006, 354(26): 2783-2793.
[18]
Rebagliato M, Murcia M, Alvarez-Pedrerol M, et al. Iodine supplementation during pregnancy and infant neuropsychological development. INMA mother and child cohort study [J]. Am J Epidemiol, 2013, 177(9): 944-953.
[19]
Andersen S, Karmisholt J, Pedersen KM, et al. Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals [J]. Br J Nutr, 2008, 99(4): 813-818.
[1] 何金梅, 尹立雪, 谭静, 张文军, 王锐, 任梅, 廖明娇. 超声心肌做功技术对2型糖尿病患者潜在左心室心肌收缩功能损伤的评价[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1029-1035.
[2] 张健, 刘小龙, 查天建, 姚俊杰, 王傑. 富含血小板血浆联合异种脱细胞真皮基质修复糖尿病足缺血性创面的临床效果[J]. 中华损伤与修复杂志(电子版), 2023, 18(06): 503-506.
[3] 崔占斌, 乔军利, 张丽丽, 韩明强. 尿碘水平与甲状腺乳头状癌患者术后复发危险度分层的相关性[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 615-618.
[4] 方钟进, 黄华生, 陈早庆, 郁兆存, 郑哲明, 谢永康, 陈仲宁, 邹演辉, 刘乾海, 陈镇宏. 负压组合式输尿管镜联合输尿管软镜与经皮肾镜治疗复杂性肾结石的比较[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 601-604.
[5] 马涛, 叶春伟, 刘滔, 彭文希, 李志鹏. 腹腔镜与开放性离断式肾盂成形术治疗小儿肾盂输尿管连接部梗阻的比较[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 605-610.
[6] 王晓丹, 王媛, 崔向宇, 任晓磊. 上尿路结石内镜手术后尿源性脓毒血症病原菌耐药及死亡高危因素分析[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 611-615.
[7] 栗霞, 孟丽, 高康, 白敏娜, 张美芬. 泌尿外科专科护士培训核心知识体系构建与应用效果[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 621-626.
[8] 刘成, 赖聪, 黄健, 王建辰, 罗茜芸, 许可慰. EDGE SP1000单孔手术机器人辅助腹腔镜下猪输尿管部分切除联合端端吻合术的可行性研究[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 642-646.
[9] 汪洋, 李志鹏, 王可兵. 上尿路尿路上皮癌术后预防性膀胱灌注化疗的研究进展[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 649-652.
[10] 黄岩, 刘晓巍, 杨春玲, 兰烨. 急性胰腺炎合并糖尿病患者的临床特征及血糖代谢与病情严重度的相关性[J]. 中华消化病与影像杂志(电子版), 2023, 13(06): 439-442.
[11] 薛念余, 张盛敏, 吴凌恒, 沙蕾, 童揽月, 沈崔琴, 李朝军, 杜联芳. 研究血清胆红素对2型糖尿病患者心脏结构发生改变前心肌功能的影响[J]. 中华临床医师杂志(电子版), 2023, 17(9): 1004-1009.
[12] 李静静, 翟蕾, 赵海平, 郑波. 多囊肾合并囊肿的多重耐药菌感染一例并文献复习[J]. 中华临床医师杂志(电子版), 2023, 17(08): 920-923.
[13] 王丽芳, 宁武, 丁艳, 张彦霞, 马豆豆, 卢哲敏, 韩芃, 李超然, 王宽婷. 北京市石景山区中学生的血尿酸与血清25(OH)D3水平的相关性研究[J]. 中华临床医师杂志(电子版), 2023, 17(08): 865-869.
[14] 张曦才, 曹先德. 经皮肾镜取石术治疗无积水肾结石中皮肾通道建立的应用研究进展[J]. 中华临床医师杂志(电子版), 2023, 17(08): 911-915.
[15] 张曦才, 曹先德, 高建萍, 沈大庆, 曹现祥, 郭诗杰, 李凤岳, 肖琳. 免人工肾积水在超声引导经皮肾镜取石术中的应用[J]. 中华临床医师杂志(电子版), 2023, 17(07): 798-803.
阅读次数
全文


摘要