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中华妇幼临床医学杂志(电子版)

中华妇幼临床医学杂志(电子版) ›› 2017, Vol. 13 ›› Issue (02) : 210 -213. doi: 10.3877/cma.j.issn.1673-5250.2017.02.016

所属专题： 文献；

论著

女性生殖道解脲脲原体感染及其药敏分析
叶麾1, 曾玺1, 邓泽文1, 江咏梅1, 郄明蓉1,†()   
  1. 1. 610041　成都，四川大学华西第二医院妇产科、出生缺陷与相关妇儿疾病教育部重点实验室
  • 收稿日期:2016-11-08 修回日期:2017-03-07 出版日期:2017-04-01
  • 通信作者: 郄明蓉

Ureaplasma urealyticum infection in female genital tract and drug sensitivity test

Hui Ye1, Xi Zeng1, Zewen Deng1, Yongmei Jiang1, Mingrong Qie1,†()   

  1. 1. Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2016-11-08 Revised:2017-03-07 Published:2017-04-01
  • Corresponding author: Mingrong Qie
  • About author:
    Corresponding author: Qie Mingrong, Email:
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引用本文：

叶麾, 曾玺, 邓泽文, 江咏梅, 郄明蓉. 女性生殖道解脲脲原体感染及其药敏分析[J]. 中华妇幼临床医学杂志(电子版), 2017, 13(02): 210-213.

Hui Ye, Xi Zeng, Zewen Deng, Yongmei Jiang, Mingrong Qie. Ureaplasma urealyticum infection in female genital tract and drug sensitivity test[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2017, 13(02): 210-213.

目的

探讨女性生殖道解脲脲原体(Uu)的感染及其耐药性。

方法

选取2015年6月至10月于四川大学华西第二医院门诊进行常规妇科体检的719例受试者的宫颈管内分泌物标本为研究对象，受试者年龄为16～48岁。同时对Uu感染情况和耐药性进行分析。

结果

①这719例进行常规妇科体检的受试者中，Uu检查结果呈阳性者为204例，阳性率为28.4%。其中25～35岁年龄段感染者为主(71.1%)。②药敏试验结果发现Uu对强力霉素、交沙霉素、四环素、普拉霉素等抗菌药物敏感，敏感度分别为97.1%、 96.1%、 95.6%、99.0%。但对氧氟沙星和环丙沙星的耐药性高，分别为76.5%和88.2%。

结论

根据药敏试验结果选择合适的抗菌药物对控制Uu感染、降低相关疾病发病率，以及保护育龄期妇女的健康具有重要意义。

关键词: 女性生殖道, 脲原体属感染, 微生物敏感性试验, 妇女
Objective

To analysis Ureaplasma urealyticum (Uu) infection in female genital tract and drug sensitivity test in order to provide a reference of using antibiotics.

Methods

From June to October, 2015, a total of 719 patients with their cervical endocrine specimens, received routine gynecological examination were enrolled into this study. Subjects aged 16 to 48 years old. Then, the infection and drug sensitivity test of Uu were analyzed.

Results

①Among 719 cases, 204 cases were infected with Uu, accounting for 28.4%. And the infection women concentrated between 25 and 35 years old, accounting for 71.1%. ②The results of drug sensitivity test showed that the Uu was susceptible to doxycycline, josamycin, tetracycline, apramycin, and the sensitive rates were 97.1%, 96.1%, 95.6%, 99.0%, respectively. However, ofloxacin and ciprofloxacin had higher drug resistance rates, and the rates were 76.5% and 88.2%, respectively.

Conclusions

Based on drug sensitivity test, appropriate antibiotics is beneficial to curbing the Uu infection and decreasing morbidity of relative diseases. It plays an important role in protecting the health of child-bearing age women.

Key words: Female genital tract, Ureaplasma infections, Microbial sensitivity tests, Women
表1 204例解脲脲原体呈阳性受试者的宫颈管分泌物对9种抗菌药物的药敏试验情况[例数(%)]
抗菌药物 高度敏感 中度敏感 耐药
强力霉素 198(97.1) 0(0) 6(2.9)
交沙霉素 196(96.1) 7(3.4) 1(0.5)
氧氟沙星 9(4.4) 39(19.1) 156(76.5)
红霉素 150(73.5) 39(19.1) 15(7.4)
四环素 195(95.6) 2(1.0) 7(3.4)
环丙沙星 5(2.5) 19(9.3) 180(88.2)
阿奇霉素 167(81.9) 30(14.7) 7(3.4)
克拉霉素 171(83.8) 24(11.8) 9(4.4)
普拉霉素 202(99.0) 0(0) 2(1.0)
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