探讨不典型川崎病(KD)患儿的临床特征、实验室检查结果、诊断及其治疗方法。

选择2000年3月至2010年12月于本院确诊及治疗的86例不典型KD患儿的临床病历资料为研究对象，对其临床症状和实验室检查结果进行回顾性分析(本研究遵循的程序符合本院人体试验委员会所制定的伦理学标准，得到该委员会批准，并与签署临床科研知情同意书)。

本组患儿均出现发热症状(100%)，出现口唇皲裂症状为51例(59.3%),皮疹为40例(46.5%)，球结膜充血为68例(79.1%)，颈部淋巴结肿大为36例(41.9%)。辅助检查结果：外周血白细胞计数增高为81例(94.2%)，血小板增高为76例(88.4%)，红细胞沉降率(ESR)增快为72例(83.7%)，C反应蛋白(CRP)增高为74例(86.0%)。74例行彩色多普勒超声心动图患儿均发现冠状动脉出现不同程度改变。

提高对不典型KD的认识，及时完善相关辅助检查，尽早明确诊断及治疗，可降低该病冠状动脉病变发生率。

To investigate the clinical features, laboratory examination, diagnosis and treatment of atypical Kawasaki disease(KD).

A total of 86 children with atypical KD who were treated in the Sichuan Provincial People's Hospital were included in the study from March 2000 to December 2010. Their clinical symptoms and results of laboratory examination were retrospective reviewed. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Sichuan Provincial People's Hospital. Informed consent was obtained from each parent.

All children showed the symptom of fever(100%). Among the 86 cases, the lips chapped symptoms showed in 51 cases (59.3%), skin rash in 40 cases (46.5%), bulbar conjunctiva congestion in 68 cases (79.1%), neck lymphadenectasis in 36 cases (41.9%). Laboratory examination results showed that white blood cells count, blood platelets, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were increased in 81 cases(94.2%), 76 cases(88.4%), 72 cases(83.7%) and 74 cases(86.0%), respectively. Varying degrees of coronary artery lesions were found in 74 cases.

Enhance the vigilance of atypical KD, consummate the correlation inspection promptly and make clear about the diagnosis and treatment as soon as possible can reduce the incidence rate of coronary artery damage in children with atypical KD.