探讨低出生体重(low birth weight，LBW)对青少年体重及心血管功能的影响，为青少年心血管疾病的早期预防提供依据。

2006年至2007年，在江苏省盐城市城区盐城卫生职业学院和盐城高等机电技术学校随机抽取1200例青少年(本研究遵循的程序符合本院人体试验委员会所制定的伦理学标准，得到该委员会批准，分组征得受试对象本人的知情同意，并与之签署临床研究知情同意书)，采集其出生时体重资料，分析该地区低出生体重发生率。从1200例青少年低出生体重者中，随机抽取20例纳入实验组，从正常出生体重者中，随机抽取20例纳入对照组，分别测量身高、体重、收缩压(systolic blood pressure，SBP)、舒张压(diastolic blood pressure，DBP)、心率(heart rate，HR)水平及心脏超声检测心功能。

1200例青少年中，低体重发生率约为11.1%(117/1055)，两组体重及体重指数(body mass index，BMI)比较，差异无显著意义(P>0.05)；收缩压、舒张压及心率水平比较，实验组高于对照组，且差异有显著意义(P<0.01)；心脏超声检测各项指标两组比较，差异无显著意义(P>0.05)。

低出生体重可增加青少年高血压、心血管疾病患病风险，心血管疾病的防治工作应从胎儿时期抓起。

To explore the effects of low birth weight (LBW) on the body weight and cardiovascular function of teenagers, and to provide theoretical basis for early intervention and prevention of fetal-borne diseases.

From 2006 to 2007, 1200 healthy teenagers who aged from 17 to 22 years old were selected randomly from Yancheng Health Vocational & Technical College and Yancheng Advanced Electrical and Technical School. Informed consent was obtained from all participants. The data of the body weight were collected and the incidence rate of low birth weight was analyzed. Among them, 20 teenagers with low birth weight were included into experiment group and other 20 with normal birth weight were randomly selected into control group. The teenagers in both groups were further examined the body height, weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and cardiac ultrasound.

The incidence rate of low body weight was 11.1% (117/1055). There had no significant difference of body weight and body mass index between two groups (P>0.05), and there had significant difference in systolic blood pressure, diastolic blood pressure, and heart rate (P<0.01). There was no statistically significant difference in the cardiac ultrasound examination (P>0.05).

The low birth weight could increase the risk of hypertension, cardiovascular diseases, so the prevention work should be conducted from fetus stages.