Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2025, Vol. 21 ›› Issue (02): 189 -194. doi: 10.3877/cma.j.issn.1673-5250.2025.02.010

Original Article

Clinical features and treatment of renal abscess in children

Jing Liu1, Yanhua Chai1, Yanbo Lai2, Liyan Ma1,()   

  1. 1. Department of Pediatrics,General Hospital of Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China
    2. Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China
  • Received:2024-12-10 Revised:2025-03-05 Published:2025-04-01
  • Corresponding author: Liyan Ma

Objective

To investigate the clinical characteristics and treatment strategies of renal abscesses in children.

Methods

A total of 5 cases of pediatric renal abscess children(child 1-5)admitted to the Department of Pediatrics,General Hospital of Ningxia Medical University from January 2022 to December 2024 were included into study.A retrospective analysis was conducted on general information,clinical manifestations,laboratory tests,imaging findings,treatment plans,and outpatient follow-up results of these 5 children.This study was approved by the Ethics Committee of the General Hospital of Ningxia Medical University (Ethics Approval No.KYLL-2025-0152),and informed consents were obtained from the guardians of the children for their diagnosis and treatment.

Results

①Among the 5 children,3 cases were male and 2 cases were female,with ages ranging from 3 to 13 years.The clinical manifestations of the 5 children were primarily characterized by recurrent fever,with some children presenting with abdominal pain,vomiting,and urinary tract irritation signs.One child exhibited tenderness on renal percussion,while no other positive physical signs were observed.②Before treatment,all 5 children had elevated peripheral blood white blood cell count(WBC),C-reactive protein (CRP),and erythrocyte sedimentation rate (ESR).Two children had increased urinary leukocytes,and one child had a positive urine culture,with the pathogen identified as Escherichia coli.③After admission,all 5 children underwent color Doppler ultrasound of the urinary system,enhanced CT of the kidneys,or MRI.Among them,left renal abscess was found in 3 children,and right renal abscess in 2 children.Upper pole abscess was present in 3 children,and lower pole abscess in 2 children.Three children had renal abscess diameters less than 3 mm,while 2 children had diameters greater than 3 mm.Three children exhibited hydronephrosis.Color Doppler ultrasound of the urinary system showed hypoechoic masses within the renal parenchyma with unclear borders,with diameters ranging from 1.7 to 5.0 cm.MRI of the kidneys revealed patchy abnormal signals within the renal parenchyma,with high signal intensity on diffusion-weighted imaging(DWI)and unclear borders;enhanced scanning showed heterogeneous enhancement of the lesions.④All children received conservative treatment.Initial treatment involved intravenous infusion of broadspectrum antibiotics (piperacillin-tazobactam,meropenem,or ertapenem)for anti-infection therapy.However,the therapeutic effect was unsatisfactory,leading to an upgrade in antibiotic treatment.⑤After discharge,all children continued oral antibiotic therapy for more than 14 days.Follow-up within 2 weeks after discharge showed complete resolution of renal abscesses without renal scar formation.No recurrence was observed during the outpatient follow-up period after discontinuation of medication.

Conclusions

The use of broad-spectrum antibiotics for the treatment of pediatric renal abscesses has proven to be effective and can be recommended as the first-line therapeutic approach.

表1 本研究5例肾脓肿患儿一般临床资料
表2 本研究5例肾脓肿患儿入院时实验室检查结果
表3 本研究5例肾脓肿患儿的影像学检查结果
患儿编号 泌尿系统彩色多普勒超声 肾脏增强CT或MRI
1 右侧肾上极脓肿,右侧肾上极实质内见2.5 cm×2.0 cm 不均匀低回声团块,无明显边界,可见小片状液化区 肾脏MRI:可见右肾实质片状异常信号灶,呈长T1混杂长T2信号,DWI呈高信号,边界不清,面积约为2.6 cm×2.0 cm,增强检查可见病灶边缘轻度强化。右肾实质上极外侧肾脓肿
2 左侧肾下极脓肿,肾盂分离,下极实质内见4.4 cm×3.1 cm 不均匀低回声包块,边界不清 肾脏MRI:见左侧肾多发斑片状长T1长T2信号影,DWI呈高信号,最大直径约为3.5 cm,增强扫描见病灶呈环形强化。考虑肾脏感染导致肾脓肿。左侧肾盂扩张,可见膀胱、输尿管反流(Ⅲ级)
3 左肾上极脓肿,肾盂分离,肾上极实质内见2.6 cm×2.0 cm 片状不均匀低回声区,边界不清 肾脏MRI:见左侧肾上极异常信号,在T2WI压脂序列上病变低信号,T1W1呈混杂稍高信号,DWI呈稍高信号影,面积约为2.6 cm×3.0 cm,增强扫描可见病灶轻度不均匀强化
4 右肾下极脓肿,左肾肾盂分离,右肾下级见1.7 cm×1.2 cm 片状不均匀低回声区,边界不清 肾脏增强CT:见右肾增大,多发类圆形稍低密度影,部分边界欠清,较大病灶直径约为1.6 cm,增强扫描可见病灶欠均匀强化,右侧肾感染性肾脓肿改变
5 左肾上极脓肿,上极见5.0 cm ×4.4 cm 不均匀低回声团块,边界不清 肾脏增强CT:见左侧肾混杂密度占位,面积约为4.0 cm×4.5 cm,边界欠清,内见低密度坏死区,增强检查可见呈肾实质中度强化,而坏死区无强化,考虑肾脏感染导致肾脓肿可能
表4 本研究5例肾脓肿患儿抗菌药物使用情况
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