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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2024, Vol. 20 ›› Issue (02): 172 -178. doi: 10.3877/cma.j.issn.1673-5250.2024.02.007

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Gut mycobiome and pediatric inflammatory bowel disease

Qing Liu1, Zhiling Wang1,†()   

  1. 1. Department of Pediatric Gastroenterology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2023-12-23 Revised:2024-03-16 Published:2024-04-01
  • Corresponding author: Zhiling Wang
  • Supported by:
    China International Medical Foundation Project(Z-2017-27-2001); Technology Project of Science and Technology Department of Sichuan Province(2022YFS0026)
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Gut mycobiome (fungi) is a crucial component of the intestinal microecosystem homeostasis. The advancement of technology contributes greatly to new research in this field. More and more pediatric gastroenterology studies have focused on the relationship between intestinal fungi and IBD. Gut mycobiome-based interventions may provide a new strategy for the treatment of IBD. In this study, we intend to elaborate the latest research status of the composition changes gut mycobiome, its potential use as biomarkers and targets for the treatment of IBD, aiming to provide reference for clinical understanding of the relationship between intestinal fungi and IBD.

Key words: Fungi, gastrointestinal, Inflammatory bowel diseases, Colitis, ulcerative, Crohn disease, Molecular targeted therapy, Candida, Malassezia, Saccharomyces cerevisiae, Child
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