Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2023, Vol. 19 ›› Issue (05): 517 -521. doi: 10.3877/cma.j.issn.1673-5250.2023.05.004

Forum

Current research status on colonization or infection and mother-to-child transmission of extended-spectrum β-lactamase-producing Enterobacteriaceae in pregnant and post-partum women

Ling Wei, Hui Li, Yi Chen()   

  1. Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
    Beijing Center for Disease Prevention and Control, Beijing 100013, China
  • Received:2023-03-19 Revised:2023-09-11 Published:2023-10-01
  • Corresponding author: Yi Chen
  • Supported by:
    Beijing Natural Science Foundation(6222017)

Extended-spectrum β-lactamase (ESBL) is a major cause of resistance to cephalosporins in Enterobacteriaceae. Since ESBL being discovered in the early 1980s, ESBL-producing Enterobacteriaceae (ESBL-PE) has spread worldwide. ESBL-PE colonization or infection in pregnant/post-partum women and its antibiotic resistance are particularly serious. ESBL-PE colonization or infection in these particular groups poses several threats both to maternal and fetal/neonatal health, and leads to adverse outcomes in mothers and neonates, which should be paid high attention by researchers of departments of obstetrics and neonatology. The authors intend to review the recent research progress on the colonization or infection and mother-to-child transmission of ESBL-PE in pregnant and post-partum women.

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