Perinatal anxiety/depression is a different manifestation of excessive stress, including pregnancy anxiety/depression and postpartum anxiety/ depression. It refers to a woman′s psychosomatic stress response to internal and external stressful events from the beginning of pregnancy to 12 months after delivery. Perinatal anxiety may develop into excessive anxiety, and excessive anxiety failure may develop into perinatal anxiety/depression. The global incidence of perinatal anxiety/depression is about 10%-21%. Perinatal anxiety/depression can increase the incidence of obstetric diseases and aggravate labor pain in women, increase the rate of maternal self-injury and suicide, and may also lead to adverse outcomes in children and families, causing serious social burdens. Therefore, it has been paid more attention in clinic. Perinatal anxiety/depression is associated with many factors, and new studies have focused on the relationship between labor pain (LP) and perinatal anxiety/depression. Existing studies have shown that anxiety/depression during pregnancy can aggravate LP, which may also continue to postpartum as postpartum anxiety/depression. However, whether LP is directly related to postpartum anxiety/depression is controversial. The author intends to elaborate the latest research status of correlation between the perinatal anxiety/depression and LP from the following three aspects: the correlation between anxiety/depression during pregnancy and LP, the correlation between LP and postpartum anxiety/depression, and the correlation between anxiety/depression during pregnancy and postpartum anxiety/depression, in order to provide a reference for related further clinical research.