Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2022, Vol. 18 ›› Issue (04): 373 -378. doi: 10.3877/cma.j.issn.1673-5250.2022.04.001

Editorial

Assessment of cardiovascular diseases in children by cardiac magnetic resonance

Hang Fu, Yingkun Guo()   

  1. Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2022-01-09 Revised:2022-07-11 Published:2022-08-01
  • Corresponding author: Yingkun Guo
  • Supported by:
    National Natural Science Foundation of China(81901712, 81771887); Clinical Research Funding of Chinese Society of Cardiology (CSC)(HFCSC2019B01)

Cardiovascular diseases (CVD) in children would cause pathophysiological disorders in cardiac structure, hemodynamics, function and myocardial tissue. Accurate assessment of these disorders is of great importance for treatment decision making, therapeutic efficacy evaluation and long-term follow-up for CVD. Based on cardiac magnetic resonance (CMR)′s advantages of high soft tissue resolution, without ionizing radiation and one-stop imaging of anatomical structure, function and myocardial tissue, CMR has become an important examination modality for children with CVD. The spin-echo pulse sequence, fast-suppressed-3D-true fast imaging with steady-state precession sequence of CMR and contrast-enhanced magnetic resonance angiography (MRA) showed good visualization of the morphology, size, interconnections of atrium, ventricles and large vessels. Phase contrast (PC) and 4D-flow of CMR can measure blood flow velocity and volume quantitatively, evaluate hemodynamic accurately, including analyze cardiac stroke volume, pulmonary blood flow/systemic blood flow, valvular reverse flow, and pressure gradient. Cine sequence of CMR can assess cardiac systolic and diastolic functions accurately. Combined with feature tissue tracking, cine sequence of CMR can also be used to early assess subclinical cardiac dysfunction by evaluating myocardial deformation. Furthermore, coronary microcirculation, myocardial fibrosis and edema can be detected quantitatively with first-pass perfusion imaging, late gadolinium enhancement (LGE), T1-mapping and T2-mapping of CMR , which could provide clinical information related to etiology, pathophysiology and prognosis for improving clinical management of children with CVD. Herein, the author intends to expound the value of CMR in diagnosis and treatment of children with CVD.

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