To explore the feasibility of cervical ripening and labor induction under the whole management during delivery.

From January 1, 2018 to December 31, 2020, a total of 848 puerperae who received whole process delivery management in labor-delivery-recovery-postpartum (LDRP) integrated ward in the Department of Obstetrics and Gynecology of Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School were selected as research subjects. According to whether in labor or not, 848 puerperae were divided into natural labor group (n=441) and induced labor group (n=407). The general clinical data, such as age, gravidity, gestational age, pregnancy complications and delivery outcomes were compared between two groups by restrospective study mehod. The procedure followed in the study met the requirements of the Helsinki Declaration of the World Medical Association revised in 2013, and had been reviewed and approved by the Ethics Committee of Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School (Approval No. 201702001).

① There were no significant differences between two group in the age, the proportion of elder pregnant women and gravidity (P>0.05). There were significantly differences in gestational age, the proportion of multiparous, the rate of premature birth, the rate of oxytocin for contraction, and the duration of entry to delivery between two groups (P<0.05). ② In induced labor group, all puerperae received prostaglandins or oxytocin in promoting cervical ripening and labor induction, and the ratios of dinoprostone, misoprostol, oxytocin, dinoprostone + misoprostol were 26.5 % (108/407), 10.3% (42/407), 60.0% (244/407), 3.2% (13/407). ③ The total cesarean section rate (2.9% vs 7.1%), episiotomy rate (20.1% vs 28.6%), neonatal birth weight [3 410 g (3 180-3 650 g) vs 3 340 g (3 040-3 640 g)] and hospital time [4 d (3-4) d vs 4 d (4-5 d)], the differences were statistically significant between two groups (χ²=7.846, χ²=7.894, Z=-0.730, Z=-5.112; P<0.05). ④ There was no significant difference in the cesarean section rate after labor, the rate of postpartum hemorrhage, bleeding volume ≥1 000 mL in 24 hours after delivery, red blood cell infusion, placing intrauterine balloon tamponade and postoperative hospital stay between two groups (P>0.05).

It is feasible to provide puerperae with cervical ripening and labor induction under the whole management during delivery for the appropriate nursing resource and standard labor induction procedure, which can obtain the improving perinatal outcomes.