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中华妇幼临床医学杂志(电子版)

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2021, Vol. 17 ›› Issue (04): 373 -379. doi: 10.3877/cma.j.issn.1673-5250.2021.04.001

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Current research status on developmental trajectory of lung in premature infants

Haiyang Zhang, Hanmin Liu()   

  • Received:2021-03-11 Revised:2021-07-13 Published:2021-08-01
  • Corresponding author: Hanmin Liu
  • Supported by:
    Key Research and Development Project of Sichuan Science and Technology Department(2019YFS0037)
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The development and maturation of human lung follows a fixed trajectory, and a variety of influencing factors in early life may lead to changes in this trajectory, thus changing the developmental outcomes of children′s respiratory system. Lung function test of premature infants can dynamically, accurately, non-invasively, early and repeatedly assess respiratory system status and understand characteristics of lung function in early life. Study on characteristics of premature infants′ lung development trajectory is helpful to better understand their respiratory system development and characteristics of their lung function transition to adult. This paper summarizes the trajectory pattern of premature infants′ lung development, and catch-up growth of premature infants′ lung development, influence factors of early life on trajectory of premature infants′ lung development and maturation, and other related studies.

Key words: Respiratory function tests, Respiratory distress syndrome, Bronchopulmonary dysplasia, Pulmonary disease, chronic obstructive, Lung development trajectory, Infant, premature
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