Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2019, Vol. 15 ›› Issue (04): 368 -372. doi: 10.3877/cma.j.issn.1673-5250.2019.04.003

Special Issue:

Forum

Current research status on molecular etiology of endometriosis

Yan Zhang1, Hongli Sun1, Xian Zhang1, Chao Chen1,()   

  1. 1. Department of Obstetrics and Gynecology, Liaocheng People′s Hospital, Liaocheng 252000, Shandong Province, China
  • Received:2019-03-29 Revised:2019-07-02 Published:2019-08-01
  • Corresponding author: Chao Chen
  • About author:
    Corresponding author: Chen Chao, Email:
  • Supported by:
    Natural Science Foundation of Shandong Province(ZR2015HL045, ZR2016CB12)

Endometriosis (EMS) is an estrogen-dependent disease in which the glands and stroma of the endometrium grow outside the uterus and is a common cause of pelvic pain and infertility. Pathogenesis of EMS has not yet been fully understood, and it is a hot topic in clinical and basic research of obstetrics and gynecology. Current studies results have shown that the molecular mechanism of EMS is not simply an abnormality of some biological characteristics. It involves the invasion of endometrium into peritoneum, angiogenesis, apoptosis, cell adhesion, autophagy and other aspects. This article focuses on latest research progresses of molecular etiology of EMS from the aspects of invasion of endometrium into peritoneum, angiogenesis, apoptosis, cell adhesion, autophagy and so on.

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