Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2019, Vol. 15 ›› Issue (04): 363 -367. doi: 10.3877/cma.j.issn.1673-5250.2019.04.002

Special Issue:

Editorials

Physiological mechanisms of delayed umbilical cord clamping on neonates: research status

Ruihan Zhong1, Huafeng Li1,()   

  1. 1. Department of Anesthesiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2019-03-08 Revised:2019-07-04 Published:2019-08-01
  • Corresponding author: Huafeng Li
  • About author:
    Corresponding author: Li Huafeng, Email:
  • Supported by:
    National Key Research & Development Program Project(2018YFC2001800); Academic Leader Training Fund Subsidized Project of Science and Technology Department of Sichuan Province(181779); Clinical Research Fund Project of West China Second University Hospital, Sichuan University(Kx086)

After the 20th century, early cord clamping become a routine operation in obstetrics domain. In recent years, however, a large number of studies have shown that delayed cord clamping (DCC) can improve the nutritional status and health outcomes of neonates, and DCC has been recommended by many internationally professional institutions and organizations including World Health Organization (WHO). Current researches indicate that DCC is extremely beneficial to neonates. For example, DCC can increase the blood volume of neonates, reduce the incidence of anemia, and reduce the incidence of complications, such as hypoxic-ischemia brain damage. However, there is no consensus on the optimal timing and other potential benefits and risks of DCC. Studies on the physiological significance of DCC to the neonates can not only confirm the physiological mechanisms of DCC, but also update the traditional concepts of health care staff about the timing of umbilical cord clamping, which contributes to the universal implementation and application of DCC. This article focuses on recent research status of the timing of DCC, DCC and placental transfusion, DCC and respiration functions of newborns, influences on newborns of DCC etc..

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