Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2018, Vol. 14 ›› Issue (04): 373 -377. doi: 10.3877/cma.j.issn.1673-5250.2018.04.001

Special Issue:

Editorial

Prenatal diagnosis and prognosis of fetal cleft lip and/or palate

Tingting Xu1, Xiaodong Wang1, Haiyan Yu1,()   

  1. 1. Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2018-01-10 Revised:2018-05-30 Published:2018-08-01
  • Corresponding author: Haiyan Yu
  • About author:
    Corresponding author: Yu Haiyan, Email:
  • Supported by:
    Training Project of Academic and Technical Leaders of Sichuan Provincial Human Resources and Social Security Department([2016]183-31); Project of Science and Technology Bureau of Chengdu(2014-HM01-00039-SF)

Cleft lip and/or palate are common facial deformities. Its etiology is still unknown, which may be due to genetic factors and environmental factors. Fetal cleft lip and/or palate can be auxiliarily diagnosed by ultrasonography and MRI. Complicated cases of fetal cleft lip and/or palate may be combined with other deformities and/or genes or chromosomal abnormalities, which affect survivors′ life quality and prognosis. So the definitive diagnosis of fetal cleft lip and/or palate is crucial. Fetal intrauterine surgery of cleft lip and/or palate is still in the research stage. The majority of non-syndromic cleft lip and/or palate (NSCL/P) can be corrected after birth by surgery in infancy. The authors intend to focus on the prenatal diagnosis and prognosis of fetal cleft lip and/or palate, in order to improve the diagnosis and treatment abilities of fetal cleft lip and/or palate.

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