Investigation and analysis of iodine nutritional status in Han and Uygur nationalities in childbearing age women in Urumqi, Xinjiang Uygur Autonomous Region

doi:10.3877/cma.j.issn.1673-5250.2017.04.017

Objective

To investigate the urinary iodine levels and differences between Han and Uygur nationalities in childbearing age women in Urumqi, Xinjiang Uygur Autonomous Region.

Methods

In May 2013, a total of 585 subjects who received epidemiological survey of thyroid disorders with complete clinical data in a community of Urumqi were chosen as research subjects. According to different nationalities, they were divided into Uygur group (n=326) and Han group (n=259). Body mass index (BMI), neck circumference, waist circumference, thyroid-stimulating hormone (TSH), thyroglobulin antibody (TgAb), and thyroid peroxidase antibody (TPOAb) levels were retrospectively analyzed. The levels of urinary iodine were determined by As³⁺ -Ce⁴⁺ catalytic spectrophotometry. This study has been approved by the ethic committee board of People′s Hospital of Xinjiang Uygur Autonomous Region.

Results

①BMI and waist circumference in Uygur group were higher than those of Han group, and the differences were statistically significant (t=7.015, 7.104; P<0.001). However, there were no significant differences between two groups in the aspects of age, neck circumference, TSH, TgAb and TPOAb levels (P>0.05). ②The median urinary iodine levels of Uygur group and Han group were 133.8 μg/L(34.1-568.2 μg/L) and 131.7 μg/L (27.7-513.6 μg/L), respectively, which showed no significant difference (Z=-0.156, P=0.876). Furthermore, there was no statistical difference between Uygur group and Han group among iodine deficiency (32.8% vs 31.3%), iodine sufficient (43.2% vs 45.2%), iodine super-sufficient (12.6% vs 14.7%), and iodine excess (11.4% vs 8.9%) (χ²=1.556, P=0.669) .

Conclusions

Part of both Uygur and Han nationality women during their childbearing age in a community in Urumqi are suffering from iodine deficiency. And there is no statistically significant difference between them in iodine nutritional status.

Key words: Iodine, Urine, Childbearing age, Uygur, Han, Women

表1 2组受试者一般临床资料比较

组别	例数	年龄(岁，±s)	BMI(kg/m^2,±s)	颈围(cm, ±s)	腹围(cm, ±s)	TSH水平[μIU/mL,M(P_2.5～P_97.5) ]	TgAb水平[IU/mL,M(P_2.5～P_97.5) ]	TPOAb水平[IU/mL，M(P_2.5～P_97.5) ]
维吾尔族组	326	35.2±6.9	25.9±4.4	33.5±7.4	83.4±11.8	2.4(0.4～14.5)	32.9(18.1～851.6)	29.7(12.4～600.0)
汉族组	259	35.6±7.0	23.7±3.2	32.6±3.7	77.3±8.9	2.4(0.4～14.5)	31.1(17.5～2 481.5)	27.3(13.3～600.0)
检验值	?	t＝－0.677	t＝7.015	t＝1.881	t＝7.104	Z＝－0.918	Z＝－1.745	Z＝－0.909
P值	?	0.391	<0.001	0.060	<0.001	0.359	0.081	0.363

表1 2组受试者一般临床资料比较

组别	例数	年龄(岁，±s)	BMI(kg/m^2,±s)	颈围(cm, ±s)	腹围(cm, ±s)	TSH水平[μIU/mL,M(P_2.5～P_97.5) ]	TgAb水平[IU/mL,M(P_2.5～P_97.5) ]	TPOAb水平[IU/mL，M(P_2.5～P_97.5) ]
维吾尔族组	326	35.2±6.9	25.9±4.4	33.5±7.4	83.4±11.8	2.4(0.4～14.5)	32.9(18.1～851.6)	29.7(12.4～600.0)
汉族组	259	35.6±7.0	23.7±3.2	32.6±3.7	77.3±8.9	2.4(0.4～14.5)	31.1(17.5～2 481.5)	27.3(13.3～600.0)
检验值	?	t＝－0.677	t＝7.015	t＝1.881	t＝7.104	Z＝－0.918	Z＝－1.745	Z＝－0.909
P值	?	0.391	<0.001	0.060	<0.001	0.359	0.081	0.363

表2 2组受试者尿碘水平及不同尿碘水平构成比比较

组别	例数	尿碘水平[μg/L，M(P_2.5～P_97.5)]	不同尿碘水平[例数(%)]
组别	例数	尿碘水平[μg/L，M(P_2.5～P_97.5)]	碘缺乏	碘适量	碘超足量	碘过量
维吾尔族组	326	133.8(34.1～568.2)	107(32.8)	141(43.2)	41(12.6)	37(11.4)
汉族组	259	131.7(27.7～513.6)	81(31.3)	117(45.2)	38(14.7)	23(8.9)
检验值	?	Z＝－0.156	χ²＝1.556
P值	?	0.876	0.669

表2 2组受试者尿碘水平及不同尿碘水平构成比比较

组别	例数	尿碘水平[μg/L，M(P_2.5～P_97.5)]	不同尿碘水平[例数(%)]
组别	例数	尿碘水平[μg/L，M(P_2.5～P_97.5)]	碘缺乏	碘适量	碘超足量	碘过量
维吾尔族组	326	133.8(34.1～568.2)	107(32.8)	141(43.2)	41(12.6)	37(11.4)
汉族组	259	131.7(27.7～513.6)	81(31.3)	117(45.2)	38(14.7)	23(8.9)
检验值	?	Z＝－0.156	χ²＝1.556
P值	?	0.876	0.669

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