Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2015, Vol. 11 ›› Issue (02): 274 -277. doi: 10.3877/cma.j.issn.1673-5250.2015.02.028

Special Issue:

Review

Research progress of correlation between inflammatory cytokines and febrile seizures in children

Na Dong1   

  1. 1. Graduate School, Inner Mongolia Medical College, Hohhot 010059, Inner Mongolia Autonomous Region, China
    2. Department of Pediatrics, Ordos Central Hospital, Ordos 017000, Inner Mongolia Autonomous Region, China
  • Received:2014-10-18 Revised:2015-01-12 Published:2015-04-01
  • About author:
    Corresponding author: Wang Aiqiong, Email:

Febrile seizures(FS) is one of the common emergency in the department of Pediatrics and the most common convulsive disorder in childhood. Among the pathogenesis of FS, inflammatory cytokines play a very important role. A large number of studies showed that inflammatory cytokines such as interleukin (IL)-1, -6, -10 and tumor necrosis factor (TNF)-α are closely related to the febrile seizures. This research focused on the correlation between inflammtory cytokines and FS in children, in order to improve the recognition of FS.

表1 单纯性与复杂性热性惊厥的鉴别要点
Table 1 Differential diagnosis between simple febrile seizures and complex febrile seizures
图1 外周血和中枢神经系统对脂多糖的反应
Figure 1 The peripheral and central nervous system response to lipopolysaccharide
图2 IL-6由多种不同的脑细胞产生,并以复杂的方式传递信号
Figure 2 IL-6 is produced by different brain cells and transferred signal in a complex manner
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