Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2015, Vol. 11 ›› Issue (01): 102 -104. doi: 10.3877/cma.j.issn.1673-5250.2015.01.024

Special Issue:

Review

Research progress of chewing gum applied in postoperative recovery of intestinal function after obstetric and gynecologic surgery

Dan Luo1, Hongwei Ma2, Yueming Yang3, Ruomei Wu1()   

  1. 1. Department of Inpatient Operating Theatre, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    2. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    3. Department of Gynecology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • Received:2014-09-12 Revised:2015-01-20 Published:2015-02-01
  • Corresponding author: Ruomei Wu
  • About author:
    Corresponding author: Wu Ruomei, Email:

Postoperative paralytic ileus is a common complication after abdominal surgery.Chewing gum has been reported to promote recovery of gastrointestinal function after abdominal surgery, shorten the first time of flatus and defecations, decrease the incidence rate of postoperative ileus and hospital stays.It's physiology mechanism maybe the cephalic-vagal pathway activation and directly or indirectly triggering the release of gastrointestinal hormones and intestinal motor function. The safety and effectiveness of chewing gum in the field of gastrointestinal surgery has been confirmed, but in the field of obstetrics and gynecology, most were abdominal surgery, the research of chewing gum applied in postoperative of obstetric and gynecologic surgery to promote recovery of gastrointestinal function and reduce postoperative complication is still in the beginning stage.We summarized the research progress of chewing gum applied in postoperative of obstetric and gynecologic surgery and presented the positive and negative opinion about it to guide the clinical practice and the future research orientation.

[1]
Quah HM,Samad A,Neathey AJ,et al. Does gum chewing reduce postoperative ileus following open colectomy for left-sided colon and rectal cancer? a prospective randomized controlled trial[J].Colorectal Dis,2006,8(1):64–70.
[2]
Matros E,Rocha F,Zinner M,et al.Does gum chewing ameliorate postoperative ileus? results of a prospective,randomized,placebo-controlled trial[J].J Am Coll Surg, 2006,202(5):773–778.
[3]
Holte K,Kehlet H. Postoperative ileus:a preventable event[J].Br J Surg,2000, 87(11):1480–1493.
[4]
Jang SY,Ju EY,Kim DE,et al. First flatus time and xerostomia associated with gum-chewing after liver resection[J].J Clin Nurs,2012,21(15-16):2188–2192.
[5]
Schuster R,Grewal N,Greaney GC,et al. Gum chewing reduces ileus after elective open sigmoid colectomy[J].Arch Surg,2006,141(2):174–176.
[6]
Vásquez W,Hernández AV,Garcia-Sabrido JL. Is gum chewing useful for ileus after elective colorectal surgery?a systematic review and meta-analysis of randomized clinical trials[J].J Gastrointest Surg,2009,13(4):649–656.
[7]
Ertas IE,Gungorduk K,Ozdemir A,et al. Influence of gum chewing on postoperative bowel activity after complete staging surgery for gynecological malignancies:a randomized controlled trial[J].Gynecol Oncol,2013,131(1):118–122.
[8]
Abd-El-Maeboud KH,Ibrahim MI,Shalaby DA,et al.Gum chewing stimulates early return of bowel motility after caesarean section[J]. BJOG,2009,116(10):1334–1339.
[9]
Kafali H,Duvan CI,Gözdemir E,et al.Influence of gum chewing on postoperative bowel activity after cesarean section[J].Gynecol Obstet Invest,2010,69(2):84–87.
[10]
靳清,黄静,宋林燕,等.咀嚼口香糖对肾脏切除术后患者胃肠功能恢复的影响[J].中华现代护理杂志,2010,16(23):2833–2834.
[11]
卢强,吴万瑞,杨罗艳,等.咀嚼口香糖对根治性膀胱切除并尿流改道患者术后肠蠕动的影响[J].中国现代医学杂志,2011,21(10):1255–1257.
[12]
Asao T,Kuwano H,Nakamura J,et al.Gum chewing enhances early recovery from postoperative ileus after laparoscopic colectomy[J].J Am Coll Surg,2002,195(1): 30–32.
[13]
Choi H,Kang SH,Yoon DK,et al.Chewing gum has a stimulatory effect on bowel motility in patients after open or robotic radical cystectomy for bladder cancer: a prospective randomized comparative study[J].Urology,2011,77(4):884–890.
[14]
Husslein H,Franz M,Gutschi M,et al. Postoperative gum chewing after gynecologic laparoscopic surgery:a randomized controlled trial[J].Obstet Gynecol,2013, 122(1):85–90.
[15]
王枭杰,池畔.咀嚼口香糖促进结直肠疾病术后肠道功能恢复的meta分析[J].中华胃肠外科杂志,2013,16(11):1078–1083.
[16]
Story SK,Chamberlain RS.A comprehensive review of evidence-based strategies to prevent and treat postoperative ileus[J].Dig Surg,2009,26(4):265–275.
[17]
Bauer AJ,Boeckxstaens GE. Mechanisms of postoperative ileus[J]. Neurogastroenterol Motil,2004,16(suppl 2):54–60.
[18]
Fanning J,Valea FA.Perioperative bowel management for gynecologic surgery[J]. Am J Obstet Gynecol,2011,205(4):309–314.
[19]
姚泰,主编.生理学.6版[M].北京:人民卫生出版社,2005:8.
[20]
Berghmans TM,Hulsewé KW,Buurman WA,et al.Stimulation of the autonomic nervous system in colorectal surgery:a study protocol for a randomized controlled trial[J].Trials,2012,13(1):93.
[21]
Tandeter H.Hypothesis:hexitols in chewing gum may play a role in reducing postoperative ileus[J].Med Hypotheses,2009,72(1):39–40.
[22]
Li S,Liu Y,Peng Q,et al.Chewing gum reduces postoperative ileus following abdominal surgery:a meta-analysis of 17 randomized controlled trials[J].J Gastroenterol Hepatol,2013,28(7):1122–1132.
[23]
韩智,赵红利,刘春容,等.子宫肌瘤患者术后咀嚼口香糖促进胃肠功能恢复的随机对照研究[J].中国医药导报,2011,8(28):37–39.
[24]
Shang H,Yang Y,Tong X,et al.Gum chewing slightly enhances early recovery from postoperative ileus after cesarean section:results of a prospective,randomized, controlled trial[J].Am J Perinatol,2010,27(5):387–391.
[25]
袁远霞,赵红利,何佳,等.剖宫产术后咀嚼口香糖促进肠道功能恢复的系统评价[J].中国循证医学杂志,2011,11(4):427–432.
[26]
Parnaby CN,MacDonald AJ,Jenkins JT.Sham feed or sham?a meta-analysis of randomized clinical trials assessing the effect of gum chewing on gut function after elective colorectal surgery[J].Int J Colorectal Dis,2009,24(5):585–592.
[27]
周飞燕,许勤,陈丽,等.胃肠术后早期咀嚼口香糖促进胃肠道功能恢复效果的系统评价[J].中华护理杂志,2012,47(9):843–846.
[28]
Milov DE,Andres JM,Erhart NA, et al. Chewing gum bezoars of the gastrointestinal tract[J].Pediatrics,1998,102(2):e22.
[29]
Njau SN.Adult sudden death caused by aspiration of chewing gum[J].Forensic Sci Int,2004,139(2-3):103–106.
[30]
Thompson AG,Razak S,Jayasinghe R.Cardiac arrest and chewing gum-an unfortunate combination[J].Med J Aust,2007,187(11-12):635.
[1] Haiping Xu, Li Sun, Kaihui Wang, Jing Lu, Chaoli Yue, Shui Wang. Application of complex decongestive therapy combined with internet nursing guidance in breast cancer-related lymphedema nursing clinic[J]. Chinese Journal of Breast Disease(Electronic Edition), 2021, 15(06): 359-365.
[2] Ruowu Ma, Yabin Guo, Qingxue Zhang, Meiqing Xie. Clinical analysis of 46, XY disorder of sex development[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2022, 18(01): 61-66.
[3] Haijian Zhao, Xin Zhao, Ning Chen, Jian Wang, Lun Zhu, Xiaoyu Zhang, Heng Li. Expression of aquaporin 3 in different states of small intestine and its clinical significance[J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(05): 342-345.
[4] Pei Yang, Peng Liu, Shaolong Hao, Yong Liu, Wei Han. Analysis of 26 cases of acute coprolite small intestinal obstruction by laparoscopy[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(03): 351-354.
[5] Jinsheng Ye, Yiping Lu, Yankai Liang, Miao Yu, Zhen Ji, Zhijian He, Honghai Zhang, Jie Wang. Clinical application of laparoscopic biological mesh to repair pelvic floor defects after rectal surgery[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2023, 17(06): 688-691.
[6] Jing Hu, Minjuan Fan, Guanhua Chi. Analysis of the occurrence and influencing factors of intra-abdominal herniated intestinal obstruction after TAPP operation[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2022, 16(04): 401-405.
[7] Haixia Zhou, Ting Nie, Yuan Jiang, Qing Tang. Effects of comprehensive nursing intervention on postoperative self-care and quality of life of patients with prostatic hyperplasia complicated with inguinal hernia[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2022, 16(02): 227-231.
[8] Xiaoyu Fan, Sizheng Sun, Yimin E, Chunzhao Yu. Different surgical options for obstructive left colon cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(06): 500-504.
[9] Lingling Wang, Haipeng Chen, Zheng Liu. The progress of occurrence, mechanism, diagnosis and treatment of peritoneal adhesions[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(02): 112-116.
[10] Qianyang Ni, Yutong Xing, Suyang Yu. A case of complex "three-way" intestinal fistula: a case report and literature review[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2022, 11(06): 521-524.
[11] Chengren Zhang, Yaochun Lv, Binbin Du, Lili Liu, Jiyong Lu, Shuai Wang, Xiongfei Yang. Comparative study between ghost ileostomy and defunctioning ileostomy in anterior resection for rectal cancer[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2022, 11(05): 377-383.
[12] Qian Geng, Qing Lu, Sha Li, Yajing Zang, Juyuan Gu. A clinical study on the promotion of lower limb functional recovery in patients after anterior cruciate ligament reconstruction by cyclic progressive rehabilitation strategy[J]. Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition), 2023, 09(02): 101-107.
[13] Zhouping Li, Xiaoyan Xue, Qingjie Xu, Yangfan Du. One case of polycythemia vera with intestinal obstruction and antiphospholipid antibody syndrome[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2022, 08(02): 180-186.
[14] Xiangzhen Cheng. Diagnosis and treatment of abdominal cocoon: Clinical analysis of nine cases with a literature review[J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(9): 968-971.
[15] Qunying Li, Liting Zheng, Yan Yu. Clinical analysis of 10 cases with a history of gynecological operation of uterine rupture in pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2023, 12(02): 98-102.
Viewed
Full text


Abstract