Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2014, Vol. 10 ›› Issue (03): 314 -319. doi: 10.3877/cma.j.issn.1673-5250.2014.03.011

Special Issue:

Original Article

Clinical Analysis of Very Low Birth Weight Infants and Extremely Birth Weight Infants

Mingyu Li1, Jun Tang,2, Jinlin Wu2, Dezhi Mu2   

  1. 1. Department of Pediatrics, Meishan Maternal and Child Health Care Hospital, Meishan 620020, Sichuan Province, China
  • Received:2014-03-03 Revised:2014-05-09 Published:2014-06-01
  • Corresponding author: Jun Tang
  • About author:
    (Corresponding author: Tang Jun, Email: )
Objective

To investigate the clinical manifestations, treatment and hospitalized outcomes of very low birth weight(VLBW) infants and extremely low birth weight(ELBW) infants.

Methods

From August 2012 to August 2013, a total of 103 cases with VLBW and ELBW in West China Second University Hospital, Sichuan University were recruited into this study. Their clinical manifestations, risk-factors of pregnant women and complications of infants were analyzed respectively. The study protocol was approved by the Ethical Review Board of Investigation of West China Second University Hospital, Sichuan University. Informed consent was obtained from all participates parents.

Results

The following were the top ten complications of 103 cases, 85 cases with neonatal pneumonia(82.5%), 79 cases with intracranial hemorrhage(ICH, 76.6%), 60 cases with hyperbilirubinemia(58.2%), 59 cases with sleep apnea(57.2%), 54 cases with respiratory failure(52.4%), 53 cases with electrolyte disturbance (51.4%), 47 cases with acid base disturbance(45.6%), 40 cases with hypoglycemia (38.8%), 38 cases with anemia (36.9%), 28 cases with neonatal respiratory distress syndrome(27.2%). In 103 cases, 84 cases (81.6%) survived, 8 cases died (7.8%, 3 cases died after withdrawing medical treatment), 11 cases (10.7%) discharged from hospital.

Conclusions

Warmth retention, nutritional support, prevention and treatment of complications can contribute to reducing the incidence of mortality in premature infants.

图1 103例VLBW儿和ELBW儿的胎龄分布
Figure 1 The gestational weeks distribution of 103 infants with VLBW and ELBW
图2 103例VLBW儿和ELBW儿母亲孕期高危因素及其发生率
Figure 2 The risk factors and their incident rates of pregnant women with VLBW and ELBW infants
图3 103例VLBW儿和ELBW儿并发症发生率
Figure 3 The incidence rate of complications of 103 infants with VLBW and ELBW
1
邵肖梅,叶鸿瑁,丘小汕,主编.实用新生儿学.4版[M].北京:人民卫生出版社,2011:46,477-482,890-891.
2
早产儿治疗用氧和视网膜病变防治指南专家组.早产儿治疗用氧和视网膜病变防治指南[J].中华儿科杂志,2007,45(9):672.
3
Claas MJ, de Vries LS, Bruinse HW. Maternal characteristics of a cohort of preterm infants with a birth weight≤750 g without major structural anomalies and chromosomal abnormalities[J]. Am J Perinatol, 2011, 28(5):367-375.
4
杜娟,王雪姣.产科因素与超低出生体重儿[J].中国实用儿科杂志,2012,27(1):1-3.
5
Fanaroff AA, Hack M, Walsh MC. The NICHD neonatal research network: changes in practice and outcomes during the first 15 years[J].Semin Perinatol, 2003, 27(2):281-287.
6
戴玉腾.极低出生体重儿22例的临床治疗[J].临床医学,2012,37(4):440-441.
7
陈春,张谦慎.超低出生体重儿救治的国内外近况[J].中国当代儿科杂志,2013,15(8):703-707.
8
姜红,宋振凤,李向红.极低出生体重儿脑室周围-脑室内出血高危因素分析[J].中国实用儿科杂志,2012,27(1):39-41.
9
Sweet DG, Carnielli V, Greisen G, et al. European consensus guidelines on the management of neonatal respiratory distress syndrome in pretern infants-2010 update[J]. Neonatology, 2010, 97(4):402-417.
10
刑燕,崔蕴璞,韩彤妍,等.11年间极低出生体重儿医院感染的临床分析[J].中华围产医学杂志,2011,14(1):39-44.
11
Cipolla D, Giuffre M, Mammina C, et al. Prevention of nosocomial infections and surve-illance of emerging resistances in NICU[J]. J Matern Fetal Neonatal Med, 2011, 24(1):23-26.
12
李杰.58例极低出生体重儿的治疗[J].中国妇幼保健,2010,25(31):4535.
13
Lavoie PM, Dube MP. Genetics of bronchpulmonary dysplasia in the age of genomics[J]. Curr Opin Pediatr, 2010, 22(2):134-138.
14
常立文,李文斌."新型"支气管肺发育不良-超低出生体重儿常见呼吸系统疾病[J].中国实用儿科杂志,2012,27(1):7-10.
15
Shah VA, Yeo CL, Ling YL, et al. Incidence, risk factors of retinopathy of prematurity among very low birth weight infants in Singapore[J]. Ann Acad Med Singapore, 2005, 34(2):169-178.
16
Chen Y, Li XX, Yin H, et al. Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China[J]. Br J Ophthalmol, 2008, 92(3):326-330.
17
丁素芳.494例新生儿中早产儿视网膜病变的发病情况[J].中国妇幼保健,2012,27(28):4405-4406.
18
陈超.超低出生体重儿视网膜病诊治进展[J].中国实用儿科杂志,2012,27(1):26-28.
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