Clinical Analysis of Very Low Birth Weight Infants and Extremely Birth Weight Infants

doi:10.3877/cma.j.issn.1673-5250.2014.03.011

Objective

To investigate the clinical manifestations, treatment and hospitalized outcomes of very low birth weight(VLBW) infants and extremely low birth weight(ELBW) infants.

Methods

From August 2012 to August 2013, a total of 103 cases with VLBW and ELBW in West China Second University Hospital, Sichuan University were recruited into this study. Their clinical manifestations, risk-factors of pregnant women and complications of infants were analyzed respectively. The study protocol was approved by the Ethical Review Board of Investigation of West China Second University Hospital, Sichuan University. Informed consent was obtained from all participates parents.

Results

The following were the top ten complications of 103 cases, 85 cases with neonatal pneumonia(82.5%), 79 cases with intracranial hemorrhage(ICH, 76.6%), 60 cases with hyperbilirubinemia(58.2%), 59 cases with sleep apnea(57.2%), 54 cases with respiratory failure(52.4%), 53 cases with electrolyte disturbance (51.4%), 47 cases with acid base disturbance(45.6%), 40 cases with hypoglycemia (38.8%), 38 cases with anemia (36.9%), 28 cases with neonatal respiratory distress syndrome(27.2%). In 103 cases, 84 cases (81.6%) survived, 8 cases died (7.8%, 3 cases died after withdrawing medical treatment), 11 cases (10.7%) discharged from hospital.

Conclusions

Warmth retention, nutritional support, prevention and treatment of complications can contribute to reducing the incidence of mortality in premature infants.

Key words: Infant, very low birth weight, Infant, extremely low birth weight, Risk factors, Mortality

图1 103例VLBW儿和ELBW儿的胎龄分布

Figure 1 The gestational weeks distribution of 103 infants with VLBW and ELBW

图2 103例VLBW儿和ELBW儿母亲孕期高危因素及其发生率

Figure 2 The risk factors and their incident rates of pregnant women with VLBW and ELBW infants

图3 103例VLBW儿和ELBW儿并发症发生率

Figure 3 The incidence rate of complications of 103 infants with VLBW and ELBW

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