Effects of Individualized Nutrition Guidance During Pregnancy on Pregnancy Outcomes and Neonatal Birth Weight

doi:10.3877/cma.j.issn.1673-5250.2014.01.021

Objective

To investigate the effects of individualized nutrition guidance during pregnancy on pregnancy outcomes and neonatal birth weight.

Methods

From June 2011 to June 2012, a cohort of 300 pregnant women with single fetal without pregnancy complications were enrolled and divided into two groups randomly. Study group (n=150) received individualized nutrition guidance during pregnancy and control group (n=150) received regular physical examination only. There had no significant differences between two groups among age, weight and height before pregnancy, and body mass index (BMI) . The pregnancy outcomes and neonatal birth weight were compared between the two groups. The study protocol was approved by the Ethical Review Board of Investigation in Maternal and Child Health Care Hospital of Gansu Province. Informed consent was obtained from all participates.

Results

There were obviously difference between study group and control group among cesarean section modes, weight gain during pregnancy and neonatal birth weight (χ²=6.72, 7.19, 16.16, P<0.05) ,but there was no obvious difference on the lateral episiotomy rate (χ²=0.21, P>0.05) .

Conclusions

Individualized nutrition guidance during pregnancy is beneficial to improving pregnancy outcomes and to controlling the weight gain during pregnancy and neonatal birth weight.

Key words: Individualized medicine, Pregnancy outcome, Weight gain, Peripartum period, Infant, newborn

表1 两组患者的一般情况比较（±s）

Table 1 Comparison of general information between two groups （±s）

组别	n	年龄(岁)	孕前体质量(kg)	身高(cm)	孕前BMI(kg/m²)
对照组	150	28.19±3.48	54.98±7.77	160.64±4.81	21.42±4.31
研究组	150	28.58±3.71	53.83 ± 7.10	159.87±4.99	20.73 ± 3.92
t		0.94	1.34	1.36	1.45
P		>0.05	>0.05	>0.05	>0.05

表1 两组患者的一般情况比较（±s）

Table 1 Comparison of general information between two groups （±s）

组别	n	年龄(岁)	孕前体质量(kg)	身高(cm)	孕前BMI(kg/m²)
对照组	150	28.19±3.48	54.98±7.77	160.64±4.81	21.42±4.31
研究组	150	28.58±3.71	53.83 ± 7.10	159.87±4.99	20.73 ± 3.92
t		0.94	1.34	1.36	1.45
P		>0.05	>0.05	>0.05	>0.05

表2 两组孕妇分娩方式比较[n（％）]

Table 2 Comparison of delivery modes between two groups [n（%）]

组别	n	阴道分娩		剖宫产分娩
研究组	150	112(74.66)		38(25.34)
对照组	150	91(60.66)		59(39.34)
χ²			6.72
P			<0.05

表2 两组孕妇分娩方式比较[n（％）]

Table 2 Comparison of delivery modes between two groups [n（%）]

组别	n	阴道分娩		剖宫产分娩
研究组	150	112(74.66)		38(25.34)
对照组	150	91(60.66)		59(39.34)
χ²			6.72
P			<0.05

表3 两组孕前BMI正常孕妇孕期体质量增长情况比较[n（%）]

Table 3 Comparison of body weight gain during pregnancy for the pregnant women with normal BMI before pregnancy[n（% ）]

组别	孕前BMI正常(n)	孕期增重
组别	孕前BMI正常(n)	增重过少	正常	增重过多
研究组	118	3(2.55)	107(90.68)	8 (6.77)
对照组	113	7(6.20)	88(77.88)	18(15.92)
χ²			7.19
P			<0.05

表3 两组孕前BMI正常孕妇孕期体质量增长情况比较[n（%）]

Table 3 Comparison of body weight gain during pregnancy for the pregnant women with normal BMI before pregnancy[n（% ）]

组别	孕前BMI正常(n)	孕期增重
组别	孕前BMI正常(n)	增重过少	正常	增重过多
研究组	118	3(2.55)	107(90.68)	8 (6.77)
对照组	113	7(6.20)	88(77.88)	18(15.92)
χ²			7.19
P			<0.05

表4 两组新生儿出生体质量的比较[n（％）]

Table 4 Comparison of birth weight between two groups [n（％）]

组别	n	LBW儿	正常	巨大儿
研究组	150	1(0.67)	144(96.00)	5 (3.33)
对照组	150	9(6.00)	123(82.00)	18(12.00)
χ²			16.16
P			<0.05

表4 两组新生儿出生体质量的比较[n（％）]

Table 4 Comparison of birth weight between two groups [n（％）]

组别	n	LBW儿	正常	巨大儿
研究组	150	1(0.67)	144(96.00)	5 (3.33)
对照组	150	9(6.00)	123(82.00)	18(12.00)
χ²			16.16
P			<0.05

[1]	赖建强，荫士安，马冠生，等．孕期妇女营养与健康状况调查[J]．营养学报，2007，29(1):4．
[2]	Dennedy MC，Dunne F．The maternal and fetal impacts of obesity and gestational diabetes on pregnancy outcome[J]．Best Pract Res Clin Endocrinol Metab，2010，24(4):573-589．
[3]	Khashan AS，Kenny LC．The effects of maternal body mass index on pregnancy outcome[J]．Eur J Epidemiol，2009，24(11):697-705．
[4]	Aviram A，Hod M，Yogev Y．Maternal obesity：implications for pregnancy outcome and long-term risks-a link to maternal nutrition[J]．Int J Gynaecol Obstet，2011，115(Suppl 1):S6-S10．
[5]	Sathyapalan T，Mellor D，Atkin SL．Obesity and gestational diabetes[J]．Semin Fetal Neonatal Med，2010，15(2):89-93．
[6]	马春玲，马润梅，芦延峰．妊娠期糖尿病与膳食的关系[J]．中国妇幼保健，2007，22(34):4804-4807．
[7]	陈敦金，余琳，李斯晨，等．妊娠期营养平衡失调与围生期并发症[J]．实用妇产科杂志，2006，22(5):260-262．
[8]	王燕，胡传来，张勤，等．孕前体质量、孕期增重对新生儿出生体质量的影响[J]．中国妇幼保健，2011，26(12):1806-1808．
[9]	Stamnes-Koepp UM，Frost L，Dahl-Joergensen K，et al．Maternal pre-pregnant body mass index，maternal weight change and offspring birthweight[J]．Acta Obstet Gynecol Scand，2012，91(2):243-249．
[10]	杨慧霞．我国产科学与胎儿医学的发展现状[J]．中华妇产科杂志，2009，44(9):6432．
[11]	周敏，章小维，渠川琐，等，妊娠期适宜增重范围与出生体质量的关系研究[J]．中国实用妇科与产科杂志，2007，23(4):275-277．
[12]	李光辉，黄醒华．医学营养治疗对糖代谢异常妊娠期患者增重及新生儿出生体质量的影响[J]．中国实用妇科与产科杂志，2007，23(4):273．
[13]	Seligman LC，Duncan BB，Branchtein L，et al．Obesity and gestational weight gain：cesarean delivery and labor complications[J]．Rev Saude Publica，2006，40(3):457-465．
[14]	李秀英，苏晓霞．个性化膳食指导对巨大儿出生率及剖宫产率的影响[J]．山东医药，2011，51(16):95-96．
[15]	Yajnik CS，Deshmukh US．Maternal nutrition，intrauterine programming and consequential risks in the offspring [J]．Rev Endocr Metab Disord，2008，9(3):203-211．
[16]	Yajnik CS，Deshmukh US．Maternal nutrition，intrauterine programming and consequential risks in the offspring [J]．Rev Endocr Metab Disord，2008，9(3):203-211．
[17]	Sullivan EL，Grayson B，Takahashi D，et al．Chronic cosumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring[J]．J Neurosci，2010，30(10):3826-3830．
[18]	虞慧君，廖晓琼，陈晓菲．孕产妇对孕期体质量认知行为的调查分析及对策[J]．中国优生与遗传杂志，2009，17(4):52-53．
[19]	中国营养学会妇幼分会．中国孕期、哺乳期妇女和1-6岁儿童膳食指南[S]．2009, 7-28．
[20]	谭永培，陆海峰．母婴健康与膳食营养60例对比分析[J]．南通医学院学报，2009，29(6):485．

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