Therapeutic Effects of Transcervical Resection of Polyp Combined With Marvelon on Endometrial Polyps

doi:10.3877/cma.j.issn.1673-5250.2012.06.021

Objective

To evaluate the therapeutic effect of transcervical resection of polyp (TCRP) combined with marvelon on endometrial polyps (EP).

Methods

From July 2007 to July 2010, 90 women with EP were included in the study, and randomly divided into research group(n=45) and control group(n=45). Research group accepted TCRP combined with marvelon for treatment, meanwhile control group accepted TCRP for treatment only. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Nanjing Branch Court of Changzheng Hospital Affiliated to Second Military Medical University.Informed consent was obtained from each patient.The menstrual circle recovery, menstrual blood volume before and after treatment, endometrial thickness and polyp relapse rate were compared between two groups.

Results

90 patients were successfully complete surgery. There had significant difference in menstrual circle recovery between two groups (χ²=4.86, P<0.05). Research group showed obvious decrease of the menstrual blood volume than that of control group(t=3.12, P<0.05). The endometrial thickness of research group was obviously smaller than that of control group(t=2.55, P<0.05), and the polyp relapse rate was less than that of control group (4.44% vs. 24.44%)(χ²=11.39, P<0.01).

Conclusions

TCRP combined with marvelon is effective in the treatment of EP, it can effectively improve menstrual disorder, and decrease polyp relapse rate.

Key words: endometrial polyps, hysteroscope, marvelon, effect

表1 两组患者月经改变情况比较[n(%)]

Table 1 Comparison of menstrual changes between two groups[n(%)]

组别	n	治疗后月经周期		月经量(±s，mL)
组别	n	正常	不正常^a	治疗前	治疗后
研究组	45	41(91.1)	4(8.9)	357.2±89.6	146.7±51.0
对照组	45	33(73.3)	12(26.7)	361.4±88.5	263.2±66.8
χ²/t	?	4.86	4.86	0.70	3.12
P	?	<0.05	<0.05	>0.05	<0.05

表1 两组患者月经改变情况比较[n(%)]

Table 1 Comparison of menstrual changes between two groups[n(%)]

组别	n	治疗后月经周期		月经量(±s，mL)
组别	n	正常	不正常^a	治疗前	治疗后
研究组	45	41(91.1)	4(8.9)	357.2±89.6	146.7±51.0
对照组	45	33(73.3)	12(26.7)	361.4±88.5	263.2±66.8
χ²/t	?	4.86	4.86	0.70	3.12
P	?	<0.05	<0.05	>0.05	<0.05

表2 两组术后子宫内膜厚度及EP复发情况比较(±s)

Table 2 Comparison of endometrial thickness and poly relapse rate between two groups after treatment(±s)

分组	n	子宫内膜平均厚度(mm)	EP复发率[n(%)]
研究组	45	7.83±1.25	2 (4.44)
对照组	45	9.80±1.13	11(24.44)
t/χ²	?	2.55	11.39
P	?	<0.05	<0.01

表2 两组术后子宫内膜厚度及EP复发情况比较(±s)

Table 2 Comparison of endometrial thickness and poly relapse rate between two groups after treatment(±s)

分组	n	子宫内膜平均厚度(mm)	EP复发率[n(%)]
研究组	45	7.83±1.25	2 (4.44)
对照组	45	9.80±1.13	11(24.44)
t/χ²	?	2.55	11.39
P	?	<0.05	<0.01

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