Analysis of Clinical Features and Antibacterial Drugs Usage in Patients With Preoperative Gynecological and Obstetrical Surgery From A Second-Grade Class-A Hospital

doi:10.3877/cma.j.issn.1673-5250.2012.05.018

Objective

To analysis the clinical features and antibacterial drugs usage in patients with preoperative gynecological and obstetrical surgery from a second-grade class-A hospital.

Methods

From June 2010 to 2011, 300 patients with preoperative gynecological and obstetrical surgery were randomly selected in the study from a second-grade class-A hospital in Shenyang. The data of clinical features was analyzed retrospectively. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Sujiatun Central Hospital.Informed consent was obtained from each patients.

Results

The average age, hospital stay and the average operation duration of 300 patients was (43.5±10.7) years old, (19.6±8.5) d and (57.3±20.7)min, respectively. There were 109 patients(36.33%) who accepted cesarean section, and 15 patients had fever(postoperative measurement, twice). The application rate of antibacterial drugs was 100.0%, and the application rate of cefoxitin was 41.33%. There were only 5 patients who accepted drug sensitivity test.

Conclusions

Management of antibacterial drugs administration for patients underwent gynecological and obstetrical surgery should be strengthened in this second-grade class-A hospital.

Key words: gynecology and obstetrics, perioperative period, clinical feature, antibacterial drug, rational use of drug

图1 本研究手术类型

Figure 1 Operation types in the research

表1 抗菌药物应用情况[n(%)]

Table 1 Application of antibacterial drugs in the research[n(%)]

药物名称	抗菌药物类型	药效学特点	应用率
头孢西丁	第2代头孢菌素类	时间依赖型	124(41.33)
甲硝唑	硝基咪唑类	浓度依赖型	96(32.00)
头孢呋辛	第2代头孢菌素类	时间依赖型	85(28.33)
依替米星	庆大霉素类	浓度依赖型	54(18.00)
奥硝唑	硝基咪唑类	浓度依赖型	54(18.00)
呋布西林	青霉素类	时间依赖型	47(15.67)
头孢噻肟	第3代头孢菌素类	时间依赖型	41(13.67)
庆大霉素	庆大霉素类	浓度依赖型	34(11.33)
美洛西林	青霉素类	时间依赖型	22 (7.33)
阿奇霉素	大环内酯类	浓度依赖型	21 (7.00)

表1 抗菌药物应用情况[n(%)]

Table 1 Application of antibacterial drugs in the research[n(%)]

药物名称	抗菌药物类型	药效学特点	应用率
头孢西丁	第2代头孢菌素类	时间依赖型	124(41.33)
甲硝唑	硝基咪唑类	浓度依赖型	96(32.00)
头孢呋辛	第2代头孢菌素类	时间依赖型	85(28.33)
依替米星	庆大霉素类	浓度依赖型	54(18.00)
奥硝唑	硝基咪唑类	浓度依赖型	54(18.00)
呋布西林	青霉素类	时间依赖型	47(15.67)
头孢噻肟	第3代头孢菌素类	时间依赖型	41(13.67)
庆大霉素	庆大霉素类	浓度依赖型	34(11.33)
美洛西林	青霉素类	时间依赖型	22 (7.33)
阿奇霉素	大环内酯类	浓度依赖型	21 (7.00)

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