To explore influence of pregnancy with hyperthyroidism on both maternal and infant and its treatment principle.

From January 2006 to December 2010, clinical data of 52 pregnant women who were diagnosed as hyperthyroidism in First People's Hospital of Foshan were included into this study, and divided into system treatment group(n=31)and non-system treatment group (n=21). The incidence rate of complications, delivery methods and the pregnancy outcomes were compared between two groups. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of First People's Hospital of Foshan. There had no significant difference between two groups among age, gravidity, parity, degree of hyperthyroidism, hyperfunction sickness indexing and body mass index (BMI) (P>0.05), respectively.

①There had significant difference between system treatment group and non-system treatment group in incidence of complications during pregnancy[16.1%(5/31)vs. 95.2%(20/21); P<0.01]. ②Artificial aiding birth rates in system treatment group were obviously lower than those in non-system treatment group [67.7% (21/31)vs. 90.5% (19/21); P<0.05]. ③It also had significantly difference between system treatment group and non-system treatment group on incidence of adverse pregnancy outcomes [29.0% (9/31)vs. 80.1% (17/21); P<0.05) ].

Positive and systematic treatment for pregnant women with hyperthyroidism has great significance on decreasing incidence of complications and improving prognosis both in maternal and infant.