Chinese Medical E-ournals Database

Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition) ›› 2011, Vol. 07 ›› Issue (02): 117 -120. doi: 10.3877/cma.j.issn.1673-5250.2011.02.008

Original Article

Analysis of Maternal Factors and Treatment of Intrauterine Fetal Death: 40 Cases

Ping ZHOU, Yuan-yuan LI, Fu-xian ZHAO   

  1. Department of Gynecology, Second People's Hospital of Yunnan Province, Kunming 650021, Yunnan Province, China
  • Published:2011-04-01
Objective

To study the maternal factors and treatment of intrauterine fetal death (IUFD).

Methods

From March 2004 to March 2010, a total of 40 cases with intrauterine fetal death were recruited into this study. They were at the age of 20~38 with the average age of 30. Among them, primipara were 32 cases (80.0%) and multipara were 8 cases (20.0%). The gestational age was 22~39 weeks with the average gestational week of 34. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Second People's Hospital of Yunnan Province. Informed consent was obtained from all participants. Maternal factors and treatment of intrauterine fetal death were analyzed retrospectively.

Results

The main cause of intruterine fetal death was obstetric complications, including hypertensive disorder complicating pregnancy (12/40, 30.0%), placenta previa (9/40, 22.5%), and placental abruption (7/22, 17.5%). Cord factors were the second main cause. Meanwhile, positive prevention the complication of disseminated intravascular coagulation (DIC).

Conclusion

Fetal hypoxic-ischemic death plays the most important role in intrauterine fetal death. The key to deal with intrauterine fetal death lies in diagnosing as early as possible, stopping pregnancy in time and treating complication being induced by fetal deaths.

1 Ddley DJ, Goldenberg R, Conway D, et al. A new system for determining the causes of still birth[J]. Obstet Gynecol, 2010, 116(2 Pt 1): 254-260.
2 Bateman BT, Simpson LL. Higher rate of stillbirth at the extremes of reproductive age: A large nationwide sample of deliveries in the United States[J]. Am J Obstet Gynecol, 2006, 194(3): 840-845.
3 Silver RM. Fetal death [J]. Obstet Gynecol, 2007, 109(1): 153-167.
4 Borghi C, Cicero AF, Degli ED, et al. Hemodynamic and neurohumoral profile in patients with different types of hypertension in pregnancy[J]. Intern Emerg Med, 2010, 30: 322.
5 Lykke JA, Langhoff-Roos J, Sibai BM, et al. Hypertensive pregnancy disorders and subsequent cardiovascular morbidity and type 2 diabetes mellitus in the mother[J]. Hypertension, 2009, 53(6): 944-951.
6 Warland J, McCutcheon H, Baghurst P. Placental position and late stillbirth: A case-control study[J]. J Clin Nurs, 2009, 18(11): 1602-1606.
7 Nayama M, Tamakloé-Azamesu D, Garba M, et al. Management in a reference Nigerien maternity. Prospective study about 118 cases during one year[J]. Gynecol Obstet Fertil, 2007, 35(10): 975-981.
8 Liu Y, Zhang ML, Zhang H. Clinical analysis of 52 cases of pregnancy associated with diabetes[J]. Shanxi Med J, 2010, 39(2): 153. [刘影,张慕玲,张红.妊娠合并糖尿病52例临床分析[J].山西医药杂志,2010, 39(2): 153.]
9 Zhou WW, Feng XJ. The effects of ureaplasma urealyticum and chlamydia infection in female genital tract on the outcomes of pregnancy[J]. Chin J Pract Gynecol Obstet, 2005, 21(11): 649.[周卫卫,冯小静.女性生殖道支原体和衣原体感染对妊娠的影响[J].中国实用妇科与产科杂志,2005, 21(11): 649.]
10 Tellefsen C, Vogt C. How important is placental examination in cases of perinatal deaths[J]? Pediatr Dev Pathol, 2010, 18: 232.
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